Mol. Cells 2011; 31(4): 355-360
Published online February 22, 2011
https://doi.org/10.1007/s10059-011-0045-3
© The Korean Society for Molecular and Cellular Biology
Hyun Nam, Jaewon Kim, Jaewan Park, Joo-Cheol Park1, Jung-Wook Kim2, Byoung-Moo Seo3, Jae Cheoun Lee4, and Gene Lee*
Correspondence to : *Correspondence: genelee@plaza.snu.ac.kr
Hertwig’s epithelial root sheath/Epithelial rests of Malassez (HERS/ERM) cells are unique epithelial cells in the periodontal ligament. They remain in periodontal tissues through- out the adult life, and it is expected that their functional role is to maintain the homeostasis of the periodontium through reciprocal interactions with other periodontal cells. In this study, we investigated whether HERS/ERM cells have primitive stem cell characteristics: those of embryonic stem cells as well as of epithelial stem cells. Primary HERS/ERM cells had typical epithelial cell morphology and characteristics and they maintained for more than five passages. They expressed epithelial stem cell-related genes: ABCG2,
Keywords embryonic stem cells, epithelial stem cells, Hertwig’s epithelial root sheath/Epithelial rests of Malassez cells, stem cell markers
Mol. Cells 2011; 31(4): 355-360
Published online April 30, 2011 https://doi.org/10.1007/s10059-011-0045-3
Copyright © The Korean Society for Molecular and Cellular Biology.
Hyun Nam, Jaewon Kim, Jaewan Park, Joo-Cheol Park1, Jung-Wook Kim2, Byoung-Moo Seo3, Jae Cheoun Lee4, and Gene Lee*
Laboratory of Molecular Genetics, Dental Research Institute, School of Dentistry, Seoul National University, Seoul 110-749, Korea, 1Department of Oral Histology-Developmental Biology, School of Dentistry, Seoul National University, Seoul 110-749, Korea, 2Department of Pediatric Dentistry, School of Dentistry, Seoul National University, Seoul 110-749, Korea, 3Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University, Seoul 110-749, Korea, 4Children’s Dental Center and CDC Baby Tooth Stem Cell Bank, Seoul 135-953, Korea
Correspondence to:*Correspondence: genelee@plaza.snu.ac.kr
Hertwig’s epithelial root sheath/Epithelial rests of Malassez (HERS/ERM) cells are unique epithelial cells in the periodontal ligament. They remain in periodontal tissues through- out the adult life, and it is expected that their functional role is to maintain the homeostasis of the periodontium through reciprocal interactions with other periodontal cells. In this study, we investigated whether HERS/ERM cells have primitive stem cell characteristics: those of embryonic stem cells as well as of epithelial stem cells. Primary HERS/ERM cells had typical epithelial cell morphology and characteristics and they maintained for more than five passages. They expressed epithelial stem cell-related genes: ABCG2,
Keywords: embryonic stem cells, epithelial stem cells, Hertwig’s epithelial root sheath/Epithelial rests of Malassez cells, stem cell markers
Young Eun Koh, Eui-Hwan Choi, Jung-Woong Kim, and Keun Pil Kim
Mol. Cells 2022; 45(11): 820-832 https://doi.org/10.14348/molcells.2022.2042Song Baek, Na Rae Han, Jung Im Yun, Jae Yeon Hwang, Minseok Kim, Choon Keun Park, Eunsong Lee, and Seung Tae Lee
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