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Mol. Cells 2010; 29(1): 57-62

Published online December 10, 2009

https://doi.org/10.1007/s10059-010-0004-4

© The Korean Society for Molecular and Cellular Biology

IFN-γ Down-Regulates TGF-β1-Induced IgA Expression through Stat1 and p300 Signaling

Seok-Rae Park1,4, Mee-Hyeun Jung1,4, Seong-Hyun Jeon2, Mi-Hee Park1, Kyoung-Hoon Park1, Mi-Ra Lee1, and Pyeung-Hyeun Kim1,3,*

1Department of Molecular Bioscience, School of Bioscience and Biotechnology, Kangwon National University, Chuncheon 200-701, Korea, 2Hans Biomed Corporation Daedeok R&D Center, Daejeon 305-390, Korea, 3Medical and Bio-material Research Center, Kangwon National University, Chuncheon 200-701, Korea, 4These authors contributed equally to this work.

Correspondence to : *Correspondence: phkim@kangwon.ac.kr

Received: July 9, 2009; Revised: September 29, 2009; Accepted: September 30, 2009

Abstract

IFN-γ has been shown to either up- or down-regulate the expression of specific TGF-β

Keywords germ-line α transcripts, IFN-γ, IgA, p300, Smad3, Stat1, TGF-β1

Article

Research Article

Mol. Cells 2010; 29(1): 57-62

Published online January 31, 2010 https://doi.org/10.1007/s10059-010-0004-4

Copyright © The Korean Society for Molecular and Cellular Biology.

IFN-γ Down-Regulates TGF-β1-Induced IgA Expression through Stat1 and p300 Signaling

Seok-Rae Park1,4, Mee-Hyeun Jung1,4, Seong-Hyun Jeon2, Mi-Hee Park1, Kyoung-Hoon Park1, Mi-Ra Lee1, and Pyeung-Hyeun Kim1,3,*

1Department of Molecular Bioscience, School of Bioscience and Biotechnology, Kangwon National University, Chuncheon 200-701, Korea, 2Hans Biomed Corporation Daedeok R&D Center, Daejeon 305-390, Korea, 3Medical and Bio-material Research Center, Kangwon National University, Chuncheon 200-701, Korea, 4These authors contributed equally to this work.

Correspondence to:*Correspondence: phkim@kangwon.ac.kr

Received: July 9, 2009; Revised: September 29, 2009; Accepted: September 30, 2009

Abstract

IFN-γ has been shown to either up- or down-regulate the expression of specific TGF-β

Keywords: germ-line α transcripts, IFN-γ, IgA, p300, Smad3, Stat1, TGF-β1

Mol. Cells
Jan 31, 2023 Vol.46 No.1, pp. 1~67
COVER PICTURE
RNAs form diverse shapes and play multiple functions as central molecules of gene expression. In this special issue on RNA, seven minireviews illustrate how basic concepts and recent RNA biology findings are transformed into new and exciting RNA therapeutics.

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