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Mol. Cells 2008; 26(1): 1-4

Published online July 31, 2008

© The Korean Society for Molecular and Cellular Biology

Training Molecularly Enabled Field Biologists to Understand Organism-Level Gene Function

Jin-Ho Kang and Ian T. Baldwin

Abstract

A gene’s influence on an organism’s Darwinian fitness ultimately determines whether it will be lost, maintained or modified by natural selection, yet biologists have few gene expression systems in which to measure whole-organism gene function. In the Department of Molecular Ecology at the Max Planck Institute for Chemical Ecology we are training “molecularly enabled field biologists” to use transformed plants silenced in the expression of environmentally regulated genes and the plant’s native habitats as “laboratories.” Research done in these natural laboratories will, we hope, increase our understanding of the function of genes at the level of the organism. Examples of the role of threonine deaminase and RNA-directed RNA polymerases illustrate the process.

Keywords Jasmonic Acid Signaling, Natural Selection, Threonine Deaminase, Darwinian Fitness, Direct Defenses, Indirect Defenses

Article

Minireview

Mol. Cells 2008; 26(1): 1-4

Published online July 31, 2008

Copyright © The Korean Society for Molecular and Cellular Biology.

Training Molecularly Enabled Field Biologists to Understand Organism-Level Gene Function

Jin-Ho Kang and Ian T. Baldwin

Abstract

A gene’s influence on an organism’s Darwinian fitness ultimately determines whether it will be lost, maintained or modified by natural selection, yet biologists have few gene expression systems in which to measure whole-organism gene function. In the Department of Molecular Ecology at the Max Planck Institute for Chemical Ecology we are training “molecularly enabled field biologists” to use transformed plants silenced in the expression of environmentally regulated genes and the plant’s native habitats as “laboratories.” Research done in these natural laboratories will, we hope, increase our understanding of the function of genes at the level of the organism. Examples of the role of threonine deaminase and RNA-directed RNA polymerases illustrate the process.

Keywords: Jasmonic Acid Signaling, Natural Selection, Threonine Deaminase, Darwinian Fitness, Direct Defenses, Indirect Defenses

Mol. Cells
Sep 30, 2021 Vol.44 No.9, pp. 627~698
COVER PICTURE
Non-mitochondrial localization of the N-terminal-deleted mutant form of ACSL1 in Cos7 cells. Green, ACSL1 mutant; Red, mitotracker; Blue, DAPI (Nan et al., pp. 637-646).

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