Research Article
Split Viewer
Mol. Cells 2003; 16(3): 278-284
Published online January 1, 1970
© The Korean Society for Molecular and Cellular Biology
Age-related Changes in the Activity of Antioxidant and Redox Enzymes in Rats
Cellular defense system, including glutathione, glu-tathione-related enzymes, and antioxidant and redox enzymes, may play crucial roles in the aging of aerobic organisms. To understand the physiological roles of these factors in the aging process, their levels were compared in the livers and brains of 5-week- and 9-month-old rats. GST activity was higher in livers and brains of 9-month-old rats than in those of 5-week-old rats, and brain catalase activity was about 2-fold higher. However, it was unchanged in the livers of the 9-month-old rats.
Keywords Aging; Antioxidant; Brain; Cellular Defense System; Liver; Rat; Redox Enzyme.
PDF
Standard view
Export citation
Share Article
Research Article
Mol. Cells 2003; 16(3): 278-284
Published online December 31, 2003
Copyright © The Korean Society for Molecular and Cellular Biology.
Age-related Changes in the Activity of Antioxidant and Redox Enzymes in Rats
Hong-Gyum Kim, Sung-Min Hong, Su-Jung Kim, Hey-Jung Park, Haeng-Im Jung, Yuk-Young Lee, Jeong-Su Moon, Hye-Won Lim, Eun-Hee Park, Chang-Jin Lim
Abstract
Cellular defense system, including glutathione, glu-tathione-related enzymes, and antioxidant and redox enzymes, may play crucial roles in the aging of aerobic organisms. To understand the physiological roles of these factors in the aging process, their levels were compared in the livers and brains of 5-week- and 9-month-old rats. GST activity was higher in livers and brains of 9-month-old rats than in those of 5-week-old rats, and brain catalase activity was about 2-fold higher. However, it was unchanged in the livers of the 9-month-old rats.
Keywords: Aging, Antioxidant, Brain, Cellular Defense System, Liver, Rat, Redox Enzyme.
Previous Article
