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Mol. Cells 2004; 18(2): 207-213

Published online January 1, 1970

© The Korean Society for Molecular and Cellular Biology

Pathogenesis-related Gene Expression by Specific Calmodulin Isoforms Is Dependent on NIM1, a Key Regulator of Systemic Acquired Resistance

Chan Young Park, Won Do Heo, Jae Hyuk Yoo, Ju Huck Lee, Min Chul Kim, Hyun Jin Chun, Byeong Cheol Moon, Ihn Hyeong Kim, Hyeong Cheol Park, Man Soo Choi, Hyun Mi Ok, Mi Sun Cheong, Sang Min Lee, Ho Soo Kim, Kon Ho Lee, Chae Oh Lim, Woo Sik Chung, Moo Je Cho

Abstract

Plants produce numerous calmodulin isoforms that exhibit differential gene expression patterns and sense different Ca2+ signals. This diversity results in different physiological responses to particular stimuli. Gm-CaM-4 and -5 are two divergent calmodulin isoforms from the soybean (Glycine max) that have been reported to be involved in plant disease resistance. However, little is known about the pathway by which these specific isoforms transduce the defense signal and up-regulate pathogenesis-related (PR) genes. Here we report that overexpression of GmCaM-4/-5 induces constitutive PR gene expression and enhances disease resistance in wild-type Arabidopsis, but not in the nim1 mutant of Arabidopsis. GmCaM-4/-5 also appear to activate trans-acting elements that bind to cis-acting elements in the Arabidopsis PR-1 promoter. Thus up-regulation of PR genes by these GmCaM isoforms is dependent on NIM1 (Non immunity 1) and unknown transcription factors.

Keywords Arabidopsis; Calmodulin; NIM1; Plant Defense; PR Gene

Article

Research Article

Mol. Cells 2004; 18(2): 207-213

Published online October 31, 2004

Copyright © The Korean Society for Molecular and Cellular Biology.

Pathogenesis-related Gene Expression by Specific Calmodulin Isoforms Is Dependent on NIM1, a Key Regulator of Systemic Acquired Resistance

Chan Young Park, Won Do Heo, Jae Hyuk Yoo, Ju Huck Lee, Min Chul Kim, Hyun Jin Chun, Byeong Cheol Moon, Ihn Hyeong Kim, Hyeong Cheol Park, Man Soo Choi, Hyun Mi Ok, Mi Sun Cheong, Sang Min Lee, Ho Soo Kim, Kon Ho Lee, Chae Oh Lim, Woo Sik Chung, Moo Je Cho

Abstract

Plants produce numerous calmodulin isoforms that exhibit differential gene expression patterns and sense different Ca2+ signals. This diversity results in different physiological responses to particular stimuli. Gm-CaM-4 and -5 are two divergent calmodulin isoforms from the soybean (Glycine max) that have been reported to be involved in plant disease resistance. However, little is known about the pathway by which these specific isoforms transduce the defense signal and up-regulate pathogenesis-related (PR) genes. Here we report that overexpression of GmCaM-4/-5 induces constitutive PR gene expression and enhances disease resistance in wild-type Arabidopsis, but not in the nim1 mutant of Arabidopsis. GmCaM-4/-5 also appear to activate trans-acting elements that bind to cis-acting elements in the Arabidopsis PR-1 promoter. Thus up-regulation of PR genes by these GmCaM isoforms is dependent on NIM1 (Non immunity 1) and unknown transcription factors.

Keywords: Arabidopsis, Calmodulin, NIM1, Plant Defense, PR Gene

Mol. Cells
Feb 28, 2023 Vol.46 No.2, pp. 69~129
COVER PICTURE
The bulk tissue is a heterogeneous mixture of various cell types, which is depicted as a skein of intertwined threads with diverse colors each of which represents a unique cell type. Single-cell omics analysis untangles efficiently the skein according to the color by providing information of molecules at individual cells and interpretation of such information based on different cell types. The molecules that can be profiled at the individual cell by single-cell omics analysis includes DNA (bottom middle), RNA (bottom right), and protein (bottom left). This special issue reviews single-cell technologies and computational methods that have been developed for the single-cell omics analysis and how they have been applied to improve our understanding of the underlying mechanisms of biological and pathological phenomena at the single-cell level.

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