Seung Hyun Oh" /> Seung Hyun Oh, Young Min Yun, Jung Eun Lee, Il Yong Kim, Jae Hoon Shin, Oh Kyeong Kweon, Hang Lee, Yeo Sung Yoon, Nam Sik Shin, and Je Kyung Seong*

" /> Seung Hyun Oh, Young Min Yun, Jung Eun Lee, Il Yong Kim, Jae Hoon Shin, Oh Kyeong Kweon, Hang Lee, Yeo Sung Yoon, Nam Sik Shin, and Je Kyung Seong*

. Mol. Cells 2011;31:351-4. https://doi.org/10.1007/s10059-011-0040-8">
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Mol. Cells 2011; 31(4): 351-354

Published online February 14, 2011

https://doi.org/10.1007/s10059-011-0040-8

© The Korean Society for Molecular and Cellular Biology

G-, R- and C-Band Patterns of Goral (Nemorhaedus caudatus) andwith Comparison to Goat (Capra hircus)

Seung Hyun Oh1,2, Young Min Yun3, Jung Eun Lee1, Il Yong Kim1, Jae Hoon Shin1, Oh Kyeong Kweon4, Hang Lee5, Yeo Sung Yoon1, Nam Sik Shin6, and Je Kyung Seong1,7,*

Author Info. +

1Laboratory of Developmental Biology and Genomics, College of Veterinary Medicine, Research Institute for Veterinary Science, and Brain Korea 21 Program for Veterinary Science, Seoul National University, Seoul 151-742, Korea, 2National Cancer Center, Koyang 410-769, Korea, 3Department of Veterinary Surgery, College of Veterinary Medicine, Jeju National University, Jeju 690-856, Korea, 4Department of Veterinary Surgery, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 151-742, Korea, 5Conservation Genome Resource Bank for Korean Wildlife (CGRB), College of Veterinary Medicine, and Brain Korea 21 Program for Veterinary Science, Seoul National University, Seoul 151- 742, Korea, 6Department of Zoo and Wild Animal Medicine, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 151-742, Korea, 7Interdisciplinary Program for Bioinformatics and Program for Cancer Biology, Seoul National University, Seoul 151-742, Korea

Correspondence to : *Correspondence: snumouse@snu.ac.kr

Received: November 5, 2011; Revised: December 23, 2011; Accepted: December 24, 2011

Abstract

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The karyotype of goral (Nemorhaedus caudatus, 2n = 56) was prepared using lymphocytes and its chromosomal band patterns were compared with those of goat (Capra hircus, 2n = 60) by CBG-, GTG- and RBG-banding tech-niques. The Sstandard karyotype of goral wasis composed of 54 acrocentric autosomes, submetacentric X chromosome, and acrocentric Y chromosome. C-bands were prominent in all autosomes except the X chromosome. G- and R-band patterns of goral wereare dissimilar to those of goat. The data support the idea It is postulated that the goral did not n’t originate from a common ancestor of bovid, or that there were numerousmany more complicated chromosomal interchanges during goral evolution, in contrast to the course of its evolution than have been observed in other bovids.

Keywords chromosome, goral, karyotype

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Research Article

Mol. Cells 2011; 31(4): 351-354

Published online April 30, 2011 https://doi.org/10.1007/s10059-011-0040-8

Copyright © The Korean Society for Molecular and Cellular Biology.

G-, R- and C-Band Patterns of Goral (Nemorhaedus caudatus) andwith Comparison to Goat (Capra hircus)

Seung Hyun Oh1,2, Young Min Yun3, Jung Eun Lee1, Il Yong Kim1, Jae Hoon Shin1, Oh Kyeong Kweon4, Hang Lee5, Yeo Sung Yoon1, Nam Sik Shin6, and Je Kyung Seong1,7,*

1Laboratory of Developmental Biology and Genomics, College of Veterinary Medicine, Research Institute for Veterinary Science, and Brain Korea 21 Program for Veterinary Science, Seoul National University, Seoul 151-742, Korea, 2National Cancer Center, Koyang 410-769, Korea, 3Department of Veterinary Surgery, College of Veterinary Medicine, Jeju National University, Jeju 690-856, Korea, 4Department of Veterinary Surgery, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 151-742, Korea, 5Conservation Genome Resource Bank for Korean Wildlife (CGRB), College of Veterinary Medicine, and Brain Korea 21 Program for Veterinary Science, Seoul National University, Seoul 151- 742, Korea, 6Department of Zoo and Wild Animal Medicine, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 151-742, Korea, 7Interdisciplinary Program for Bioinformatics and Program for Cancer Biology, Seoul National University, Seoul 151-742, Korea

Correspondence to:*Correspondence: snumouse@snu.ac.kr

Received: November 5, 2011; Revised: December 23, 2011; Accepted: December 24, 2011

Abstract

The karyotype of goral (Nemorhaedus caudatus, 2n = 56) was prepared using lymphocytes and its chromosomal band patterns were compared with those of goat (Capra hircus, 2n = 60) by CBG-, GTG- and RBG-banding tech-niques. The Sstandard karyotype of goral wasis composed of 54 acrocentric autosomes, submetacentric X chromosome, and acrocentric Y chromosome. C-bands were prominent in all autosomes except the X chromosome. G- and R-band patterns of goral wereare dissimilar to those of goat. The data support the idea It is postulated that the goral did not n’t originate from a common ancestor of bovid, or that there were numerousmany more complicated chromosomal interchanges during goral evolution, in contrast to the course of its evolution than have been observed in other bovids.

Keywords: chromosome, goral, karyotype

Mol. Cells
Sep 30, 2023 Vol.46 No.9, pp. 527~572
COVER PICTURE
Chronic obstructive pulmonary disease (COPD) is marked by airspace enlargement (emphysema) and small airway fibrosis, leading to airflow obstruction and eventual respiratory failure. Shown is a microphotograph of hematoxylin and eosin (H&E)-stained histological sections of the enlarged alveoli as an indicator of emphysema. Piao et al. (pp. 558-572) demonstrate that recombinant human hyaluronan and proteoglycan link protein 1 (rhHAPLN1) significantly reduces the extended airspaces of the emphysematous alveoli by increasing the levels of TGF-β receptor I and SIRT1/6, as a previously unrecognized mechanism in human alveolar epithelial cells, and consequently mitigates COPD.
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