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Fig. 5. Kcnma1 regulates β-catenin expression via canonical Wnt signaling. (A and B) Protein expression and quantitative analysis of β-catenin, Axin1 and USP7 in bone tissues from Osterix-Cre(–); Kcnma1f/f and Osterix-Cre(+); Kcnma1f/f mice. (C and D) western blot analysis of β-catenin, Runx2 and phosphorylated levels of GSK3β in osteoblasts isolated from the indicated mice. (E and F) Protein expression levels and quantitative analysis by western blot of Axin1 and USP7 in osteoblasts. Data are presented as mean ± SD. *P < 0.05, **P < 0.01.
Mol. Cells 2021;44:557~568
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