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Fig. 3. Developmental factors identified for functional inhibitory circuits in OB. Schematic representation of the birthdate-order dependent interneuron final positioning in the OB. The X-axis represents the birthdate and the Y-axis represents the final positions from the SVZ to target layers in the OB. For the correct positioning, each neuron underlies the distinct molecular machinery. Postnatal early-born interneurons (green cell) have active Abl1-Dcx signaling as migratory machinery for integration into the sGCL (green layer). sGCL-specific circuits perform innate olfactory functions, such as detection or sensitivity.
Mol. Cells 2020;43:215~221 https://doi.org/10.14348/molcells.2020.0033
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