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Fig. 1. Distinct features of OB interneurons development. Developmental characteristics of OB interneurons. a) OB has a higher conserved ratio of interneurons (I; orange) to excitatory neurons (E; green). b) Neurogenesis of OB interneurons throughout life. The red graph indicates the production timeline of OB interneurons. The blue graph indicates that of cortical interneurons. c) Long migration from the SVZ into the OB. Left: The MGE (orange line) mainly produces cortical interneurons. They migrate longer than excitatory precursors (green line). Right: During the postnatal stage, OB interneurons are consistently generated from the SVZ and migrate a very long distance into the OB. Orange circles: early-born interneurons, Yellow circles: late-born interneurons.
Mol. Cells 2020;43:215~221
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