Molecules and Cells

Download original image

Fig. 3. Co-mutations of RUNX1 and NF1 contribute to blood malignancy. RUNX1 t(8;21) translocation (RUNX1-ETO) represses NF1 to develop AML. RUNX1 mutation or NF1/RAS-RUNX1 co-mutation develop AML or MDS through clonal selection and cell proliferation.
Mol. Cells 2020;43:153~159
© Mol. Cells
© The Korean Society for Molecular and Cellular Biology. Powered by INFOrang Co., Ltd