Molecules and Cells

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Fig. 1. The INK4a/ARF/INK4b locus encodes potent tumor suppressors including p15ink4b, p16ink4a and p14ARF. ARF stimulates cellular senescence and apoptosis through p53-dependent or -independent pathway, thus suppressing the tumor formation.
Mol. Cells 2018;41:381~389 https://doi.org/10.14348/molcells.2018.0100
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