Genome-Wide Analysis of DNA Methylation before-and after Exercise in the Thoroughbred Horse with MeDIP-Seq

Jeong-An Gim^1,14, Chang Pyo Hong^2,14, Dae-Soo Kim³, Jae-Woo Moon², Yuri Choi¹, Jungwoo Eo¹, Yun-Jeong Kwon¹, Ja-Rang Lee¹, Yi-Deun Jung¹, Jin-Han Bae¹, Bong-Hwan Choi⁴, Junsu Ko², Sanghoon Song², Kung Ahn², Hong-Seok Ha⁵, Young Mok Yang⁶, Hak-Kyo Lee⁷, Kyung-Do Park⁷, Kyoung-Tag Do⁸, Kyudong Han⁹, Joo Mi Yi¹⁰, Hee-Jae Cha¹¹, Selvam Ayarpadikannan¹, Byung-Wook Cho¹², Jong Bhak^2,13,*, and Heui-Soo Kim^1,*

¹Department of Biological Sciences, College of Natural Sciences, Pusan National University, Busan 609-735, Korea, ²TBI, Theragen BiO Institute, TheragenEtex, Suwon 443-270, Korea, ³Genome Resource Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 305-806, Korea, ⁴Division of Animal Genomics and Bioinformatics, National Institute of Animal Science, Rural Development Administration, Suwon 441-706, Korea, ⁵Department of Genetics, Human Genetics Institute of New Jersey, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA, ⁶Department of Pathology, School of Medicine, and Institute of Biomedical Science and Technology, Konkuk University, Seoul 143-701, Korea, ⁷Department of Biotechnology, Hankyong National University, Anseong 456-749, Korea, ⁸Department of Equine Sciences, Sorabol College, Gyeongju 780-711, Korea, ⁹Department of Nanobiomedical Science and WCU Research Center, Dankook University, Cheonan 330-714, Korea, ¹⁰Research Center, Dongnam Institute of Radiological and Medical Science (DIRAMS), Busan 619-953, Korea, ¹¹Departments of Parasitology and Genetics, Kosin University College of Medicine, Busan 602-702, Korea, ¹²Department of Animal Science, College of Life Sciences, Pusan National University, Miryang 627-702, Korea, ¹³BioMedical Engineering, UNIST, Ulsan 689-798, Korea, ¹⁴These authors contributed equally to this work.