Molecules and Cells

Cited by CrossRef (112)

  1. Holly Yu Chen, Emily Welby, Tiansen Li, Anand Swaroop, Meral Gunay-Aygun. Retinal disease in ciliopathies: Recent advances with a focus on stem cell-based therapies. TRD 2019;4:97
    https://doi.org/10.3233/TRD-190038
  2. Laura Vuolo, Nicola L. Stevenson, Aakash G. Mukhopadhyay, Anthony J. Roberts, David J. Stephens. Cytoplasmic dynein-2 at a glance. 2020;133
    https://doi.org/10.1242/jcs.240614
  3. Ke Ning, Emilie Song, Brent E. Sendayen, Philipp P. Prosseda, Kun‐Che Chang, Alireza Ghaffarieh, Jorge A. Alvarado, Biao Wang, Kathryn M. Haider, Nicolas F. Berbari, Yang Hu, Yang Sun. Defective INPP5E distribution in NPHP1‐related Senior–Loken syndrome. Molec Gen & Gen Med 2021;9
    https://doi.org/10.1002/mgg3.1566
  4. Manuela Morleo, Helena L.A. Vieira, Petra Pennekamp, Alessandro Palma, Liliana Bento-Lopes, Heymut Omran, Susana S. Lopes, Duarte C. Barral, Brunella Franco. Crosstalk between cilia and autophagy: implication for human diseases. Autophagy 2023;19:24
    https://doi.org/10.1080/15548627.2022.2067383
  5. Maria Giovanna Riparbelli, Veronica Persico, Romano Dallai, Giuliano Callaini. Centrioles and Ciliary Structures during Male Gametogenesis in Hexapoda: Discovery of New Models. Cells 2020;9:744
    https://doi.org/10.3390/cells9030744
  6. Elena A. May, Tommy J. Sroka, David U. Mick. Phosphorylation and Ubiquitylation Regulate Protein Trafficking, Signaling, and the Biogenesis of Primary Cilia. Front. Cell Dev. Biol. 2021;9
    https://doi.org/10.3389/fcell.2021.664279
  7. Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs. Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss. Cells 2020;9:931
    https://doi.org/10.3390/cells9040931
  8. Zhimao Wu, Nan Pang, Yingying Zhang, Huicheng Chen, Ying Peng, Jingyan Fu, Qing Wei, Renata Basto. CEP290 is essential for the initiation of ciliary transition zone assembly. PLoS Biol 2020;18:e3001034
    https://doi.org/10.1371/journal.pbio.3001034
  9. Mary Mirvis, Tim Stearns, W. James Nelson. Cilium structure, assembly, and disassembly regulated by the cytoskeleton. 2018;475:2329
    https://doi.org/10.1042/BCJ20170453
  10. Catalina Kretschmar, María Paz Hernández-Cáceres, Montserrat Reyes, Daniel Peña-Oyarzún, Camila García-Navarrete, Rodrigo Troncoso, Francisco Díaz-Castro, Mauricio Budini, Eugenia Morselli, Jaime A. Riquelme, Joseph A. Hill, Sergio Lavandero, Alfredo Criollo. Cilia: From Mechanisms to Disease - Part B. 2018.
    https://doi.org/10.1016/bs.mcb.2022.12.013
  11. Carolyn M. Ott. The Liver. 2018.
    https://doi.org/10.1002/9781119436812.ch5
  12. Elena A. May, Marian Kalocsay, Inès Galtier D’Auriac, Patrick S. Schuster, Steven P. Gygi, Maxence V. Nachury, David U. Mick. Time-resolved proteomics profiling of the ciliary Hedgehog response. 2021;220
    https://doi.org/10.1083/jcb.202007207
  13. Peter Vogel, Laura J. Janke. Pathology of Genetically Engineered and Other Mutant Mice. 2021.
    https://doi.org/10.1002/9781119624608.ch6
  14. Jean-André Lapart, Amélie Billon, Jean-Luc Duteyrat, Joëlle Thomas, Bénédicte Durand. Role of DZIP1–CBY–FAM92 transition zone complex in the basal body to membrane attachment and ciliary budding. 2020;48:1067
    https://doi.org/10.1042/BST20191007
  15. Misato Okazaki, Takuya Kobayashi, Shuhei Chiba, Ryota Takei, Luxiaoxue Liang, Kazuhisa Nakayama, Yohei Katoh, Xueliang Zhu. Formation of the B9-domain protein complex MKS1–B9D2–B9D1 is essential as a diffusion barrier for ciliary membrane proteins. MBoC 2020;31:2259
    https://doi.org/10.1091/mbc.E20-03-0208
  16. Melissa E. Truong, Sara Bilekova, Semil P. Choksi, Wan Li, Lukasz J. Bugaj, Ke Xu, Jeremy F. Reiter. Vertebrate cells differentially interpret ciliary and extraciliary cAMP. Cell 2021;184:2911
    https://doi.org/10.1016/j.cell.2021.04.002
  17. Jinghua Hu, Peter C. Harris. Regulation of polycystin expression, maturation and trafficking. Cellular Signalling 2020;72:109630
    https://doi.org/10.1016/j.cellsig.2020.109630
  18. Hantian Qiu, Sayaka Fujisawa, Shohei Nozaki, Yohei Katoh, Kazuhisa Nakayama. Interaction of INPP5E with ARL13B is essential for its ciliary membrane retention but dispensable for its ciliary entry. 2020
    https://doi.org/10.1242/bio.057653
  19. Anna Osinka, Martyna Poprzeczko, Magdalena M. Zielinska, Hanna Fabczak, Ewa Joachimiak, Dorota Wloga. Ciliary Proteins: Filling the Gaps. Recent Advances in Deciphering the Protein Composition of Motile Ciliary Complexes. Cells 2019;8:730
    https://doi.org/10.3390/cells8070730
  20. Melis Dilara Arslanhan, Dila Gulensoy, Elif Nur Firat-Karalar. A Proximity Mapping Journey into the Biology of the Mammalian Centrosome/Cilium Complex. Cells 2020;9:1390
    https://doi.org/10.3390/cells9061390
  21. Rute Pereira, Mário Sousa. Morphological and Molecular Bases of Male Infertility: A Closer Look at Sperm Flagellum. Genes 2023;14:383
    https://doi.org/10.3390/genes14020383
  22. Koshi Tasaki, Zhuang Zhou, Yamato Ishida, Yohei Katoh, Kazuhisa Nakayama. Compound heterozygous IFT81 variations in a skeletal ciliopathy patient cause Bardet–Biedl syndrome-like ciliary defects. 2023;32:2887
    https://doi.org/10.1093/hmg/ddad112
  23. Kelsey R. Clearman, Courtney J. Haycraft, Mandy J. Croyle, James F. Collawn, Bradley K. Yoder. . 2023.
    https://doi.org/10.1016/bs.ctdb.2023.07.001
  24. Shashank Arora, Mausam Rana, Ananya Sachdev, Jacinta S D’Souza. Appearing and disappearing acts of cilia. J Biosci 2023;48
    https://doi.org/10.1007/s12038-023-00326-6
  25. Antonia Wiegering, Ulrich Rüther, Christoph Gerhardt. The ciliary protein Rpgrip1l in development and disease. Developmental Biology 2018;442:60
    https://doi.org/10.1016/j.ydbio.2018.07.024
  26. Deniz Conkar, Elif Nur Firat‐Karalar. Microtubule‐associated proteins and emerging links to primary cilium structure, assembly, maintenance, and disassembly. The FEBS Journal 2021;288:786
    https://doi.org/10.1111/febs.15473
  27. Karen I Lange, Sunayna Best, Sofia Tsiropoulou, Ian Berry, Colin A Johnson, Oliver E Blacque. Interpreting ciliopathy-associated missense variants of uncertain significance (VUS) in Caenorhabditis elegans . 2022;31:1574
    https://doi.org/10.1093/hmg/ddab344
  28. Vasiliki Karalis, Kathleen E. Donovan, Mustafa Sahin. Primary Cilia Dysfunction in Neurodevelopmental Disorders beyond Ciliopathies. JDB 2022;10:54
    https://doi.org/10.3390/jdb10040054
  29. Wen-Ting Yang, Shi-Rong Hong, Kai He, Kun Ling, Kritika Shaiv, JingHua Hu, Yu-Chun Lin. The Emerging Roles of Axonemal Glutamylation in Regulation of Cilia Architecture and Functions. Front. Cell Dev. Biol. 2021;9
    https://doi.org/10.3389/fcell.2021.622302
  30. Chao Xie, Julien C. Habif, Kirill Ukhanov, Cedric R. Uytingco, Lian Zhang, Robert J. Campbell, Jeffrey R. Martens. Reversal of ciliary mechanisms of disassembly rescues olfactory dysfunction in ciliopathies. 2022;7
    https://doi.org/10.1172/jci.insight.158736
  31. Fan Ye, Andrew R. Nager, Maxence V. Nachury. BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone. 2018;217:1847
    https://doi.org/10.1083/jcb.201709041
  32. Alind Gupta, Lacramioara Fabian, Julie A. Brill. Phosphatidylinositol 4,5-bisphosphate regulates cilium transition zone maturation in Drosophila melanogaster . 2018
    https://doi.org/10.1242/jcs.218297
  33. Xiaoyu Tian, Huijie Zhao, Jun Zhou. Organization, functions, and mechanisms of the BBSome in development, ciliopathies, and beyond. 2023;12
    https://doi.org/10.7554/eLife.87623
  34. Westley Heydeck, Brian A. Bayless, Alexander J. Stemm-Wolf, Eileen T. O'Toole, Amy S. Fabritius, Courtney Ozzello, Marina Nguyen, Mark Winey. Tetrahymena Poc5 is a transient basal body component that is important for basal body maturation. 2020
    https://doi.org/10.1242/jcs.240838
  35. Wei Wang, Brittany M. Jack, Henry H. Wang, Matthew A. Kavanaugh, Robin L. Maser, Pamela V. Tran. Intraflagellar Transport Proteins as Regulators of Primary Cilia Length. Front. Cell Dev. Biol. 2021;9
    https://doi.org/10.3389/fcell.2021.661350
  36. Ezgi Odabasi, Deniz Conkar, Jovana Deretic, Umut Batman, Kari-Anne M. Frikstad, Sebastian Patzke, Elif Nur Firat-Karalar. CCDC66 regulates primary cilium length and signaling via interactions with transition zone and axonemal proteins. 2023;136
    https://doi.org/10.1242/jcs.260327
  37. Paula Moreno-Cruz, Yaiza Corral Nieto, Laura Manrique Garcia, Amanda Gabrielly Pereira, José Manuel Bravo-San Pedro. Cilia: From Mechanisms to Disease - Part A. 2023.
    https://doi.org/10.1016/bs.mcb.2022.10.002
  38. Madison Atkins, Jiří Týč, Shahaan Shafiq, Manu Ahmed, Eloïse Bertiaux, Artur Leonel De Castro Neto, Jack Sunter, Philippe Bastin, Samuel Dale Dean, Sue Vaughan. CEP164C regulates flagellum length in stable flagella. 2021;220
    https://doi.org/10.1083/jcb.202001160
  39. Laura Girardet, Céline Augière, Marie‐Pier Asselin, Clémence Belleannée. Primary cilia: biosensors of the male reproductive tract. Andrology 2019;7:588
    https://doi.org/10.1111/andr.12650
  40. John Copeland. Actin-based regulation of ciliogenesis – The long and the short of it. Seminars in Cell & Developmental Biology 2020;102:132
    https://doi.org/10.1016/j.semcdb.2019.12.005
  41. Tiffany Yu, Miho Matsuda. Epb41l5 interacts with IQCB1 and regulates ciliary function in zebrafish embryos. 2020
    https://doi.org/10.1242/jcs.240648
  42. Hiroko Saito, Fumiko Matsukawa-Usami, Toshihiko Fujimori, Toshiya Kimura, Takahiro Ide, Takaki Yamamoto, Tatsuo Shibata, Kenta Onoue, Satoko Okayama, Shigenobu Yonemura, Kazuyo Misaki, Yurina Soba, Yasutaka Kakui, Masamitsu Sato, Mika Toya, Masatoshi Takeichi, Alpha Yap. Tracheal motile cilia in mice require CAMSAP3 for the formation of central microtubule pair and coordinated beating. MBoC 2021;32:ar12
    https://doi.org/10.1091/mbc.E21-06-0303
  43. Larissa L Dougherty, Soumita Dutta, Prachee Avasthi. The ERK activator, BCI, inhibits ciliogenesis and causes defects in motor behavior, ciliary gating, and cytoskeletal rearrangement. Life Sci. Alliance 2023;6:e202301899
    https://doi.org/10.26508/lsa.202301899
  44. Christiane Pleuger, Mari S Lehti, Jessica EM Dunleavy, Daniela Fietz, Moira K O’Bryan. Haploid male germ cells—the Grand Central Station of protein transport. 2020;26:474
    https://doi.org/10.1093/humupd/dmaa004
  45. Kazuhisa Nakayama, Yohei Katoh. Architecture of the IFT ciliary trafficking machinery and interplay between its components. Critical Reviews in Biochemistry and Molecular Biology 2020;55:179
    https://doi.org/10.1080/10409238.2020.1768206
  46. Timothy S McClintock, Naazneen Khan, Chao Xie, Jeffrey R Martens. Maturation of the Olfactory Sensory Neuron and Its Cilia. 2020;45:805
    https://doi.org/10.1093/chemse/bjaa070
  47. Jean-André Lapart, Marco Gottardo, Elisabeth Cortier, Jean-Luc Duteyrat, Céline Augière, Alain Mangé, Julie Jerber, Jérôme Solassol, Jay Gopalakrishnan, Joëlle Thomas, Bénédicte Durand. Dzip1 and Fam92 form a ciliary transition zone complex with cell type specific roles in Drosophila. 2019;8
    https://doi.org/10.7554/eLife.49307
  48. Khaled Bouhouche, Pierrick Le Borgne, Michel Lemullois, Anne-Marie Tassin. La paramécie, un organisme modèle pour étudier la ciliogenèse et les maladies ciliaires. Med Sci (Paris) 2021;37:632
    https://doi.org/10.1051/medsci/2021087
  49. Kaiqing Zhang, Fabio Da Silva, Carina Seidl, Michaela Wilsch-Bräuninger, Jessica Herbst, Wieland B. Huttner, Christof Niehrs. Primary cilia are WNT-transducing organelles whose biogenesis is controlled by a WNT-PP1 axis. Developmental Cell 2023;58:139
    https://doi.org/10.1016/j.devcel.2022.12.006
  50. Sarah E. Conduit, Elizabeth M. Davies, Alex J. Fulcher, Viola Oorschot, Christina A. Mitchell. Superresolution Microscopy Reveals Distinct Phosphoinositide Subdomains Within the Cilia Transition Zone. Front. Cell Dev. Biol. 2021;9
    https://doi.org/10.3389/fcell.2021.634649
  51. Priya Dutta, Krishanu Ray. Ciliary membrane, localised lipid modification and cilia function. Journal Cellular Physiology 2022;237:2613
    https://doi.org/10.1002/jcp.30787
  52. Nina Schweizer, Jens Lüders. From tip to toe – dressing centrioles in γTuRC. 2021;134
    https://doi.org/10.1242/jcs.258397
  53. Maxence V. Nachury, David U. Mick. Establishing and regulating the composition of cilia for signal transduction. Nat Rev Mol Cell Biol 2019;20:389
    https://doi.org/10.1038/s41580-019-0116-4
  54. Yuta Tsurumi, Yuki Hamada, Yohei Katoh, Kazuhisa Nakayama, Xueliang Zhu. Interactions of the dynein-2 intermediate chain WDR34 with the light chains are required for ciliary retrograde protein trafficking. MBoC 2019;30:658
    https://doi.org/10.1091/mbc.E18-10-0678
  55. Huijie Zhao, Qingxia Chen, Fan Li, Lihong Cui, Lele Xie, Qiongping Huang, Xin Liang, Jun Zhou, Xiumin Yan, Xueliang Zhu. Fibrogranular materials function as organizers to ensure the fidelity of multiciliary assembly. Nat Commun 2021;12
    https://doi.org/10.1038/s41467-021-21506-8
  56. Sayaka Fujisawa, Hantian Qiu, Shohei Nozaki, Shuhei Chiba, Yohei Katoh, Kazuhisa Nakayama. ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane. 2021;10
    https://doi.org/10.1242/bio.058843
  57. Jeffrey D. Amack. Structures and functions of cilia during vertebrate embryo development. Molecular Reproduction Devel 2022;89:579
    https://doi.org/10.1002/mrd.23650
  58. Chao Xie, Jeffrey R Martens. Potential Therapeutic Targets for Olfactory Dysfunction in Ciliopathies Beyond Single-Gene Replacement. 2021;46
    https://doi.org/10.1093/chemse/bjab010
  59. Kwangjin Park, Michel R Leroux. Composition, organization and mechanisms of the transition zone, a gate for the cilium. EMBO Reports 2022;23
    https://doi.org/10.15252/embr.202255420
  60. Erum A. Hartung, Lisa M. Guay-Woodford. DZIP1L defines a new functional zip code for autosomal recessive PKD. Nat Rev Nephrol 2017;13:519
    https://doi.org/10.1038/nrneph.2017.102
  61. Hyeong-Gon Yu. Inherited Retinal Disease. 2017.
    https://doi.org/10.1007/978-981-16-7337-5_4
  62. Abrar Choudhury, Neil M. Neumann, David R. Raleigh, Ursula E. Lang. Clinical Implications of Primary Cilia in Skin Cancer. Dermatol Ther (Heidelb) 2020;10:233
    https://doi.org/10.1007/s13555-020-00355-1
  63. Sarah E. Conduit, Bart Vanhaesebroeck. Phosphoinositide lipids in primary cilia biology. 2020;477:3541
    https://doi.org/10.1042/BCJ20200277
  64. Michal Niziolek, Marta Bicka, Anna Osinka, Zuzanna Samsel, Justyna Sekretarska, Martyna Poprzeczko, Rafal Bazan, Hanna Fabczak, Ewa Joachimiak, Dorota Wloga. PCD Genes—From Patients to Model Organisms and Back to Humans. IJMS 2022;23:1749
    https://doi.org/10.3390/ijms23031749
  65. José Manuel Bravo-San Pedro. Cilia: From Mechanisms to Disease - Part A. 2022.
    https://doi.org/10.1016/S0091-679X(23)00074-2
  66. Shabarni Gupta, Justyna E. Ozimek-Kulik, Jacqueline Kathleen Phillips. Nephronophthisis-Pathobiology and Molecular Pathogenesis of a Rare Kidney Genetic Disease. Genes 2021;12:1762
    https://doi.org/10.3390/genes12111762
  67. Chuan Chen, Jinghua Hu, Kun Ling. The Role of Primary Cilia-Associated Phosphoinositide Signaling in Development. JDB 2022;10:51
    https://doi.org/10.3390/jdb10040051
  68. Cassandra L. Barnes, Himanshu Malhotra, Peter D. Calvert. Compartmentalization of Photoreceptor Sensory Cilia. Front. Cell Dev. Biol. 2021;9
    https://doi.org/10.3389/fcell.2021.636737
  69. Ciaran G. Morrison. Primary cilia and the DNA damage response: linking a cellular antenna and nuclear signals. 2021;49:829
    https://doi.org/10.1042/BST20200751
  70. José Manuel Bravo-San Pedro. Cilia: From Mechanisms to Disease - Part B. 2021.
    https://doi.org/10.1016/S0091-679X(23)00097-3
  71. Garrett A. Greenan, Ronald D. Vale, David A. Agard. Electron cryotomography of intact motile cilia defines the basal body to axoneme transition. 2020;219
    https://doi.org/10.1083/jcb.201907060
  72. Steffen-Alexander Sailer, Martin D. Burkhalter, Melanie Philipp. Cholesterol and PI(4,5)P2 in Vital Biological Functions. 2020.
    https://doi.org/10.1007/978-3-031-21547-6_4
  73. Melissa A. Parisi, Meral Gunay-Aygun. The molecular genetics of Joubert syndrome and related ciliopathies: The challenges of genetic and phenotypic heterogeneity. TRD 2019;4:25
    https://doi.org/10.3233/TRD-190041
  74. Marco Gottardo, Veronica Persico, Giuliano Callaini, Maria Giovanna Riparbelli. The “transition zone” of the cilium-like regions in the Drosophila spermatocytes and the role of the C-tubule in axoneme assembly. Experimental Cell Research 2018;371:262
    https://doi.org/10.1016/j.yexcr.2018.08.020
  75. Sidney T. Ley, Wissam A. AbouAlaiwi. Basic and Clinical Understanding of Microcirculation. 2018.
    https://doi.org/10.5772/intechopen.89680
  76. Daniel Epting, Eva Decker, Elisabeth Ott, Tobias Eisenberger, Ingrid Bader, Nadine Bachmann, Carsten Bergmann. The ciliary transition zone protein TMEM218 synergistically interacts with the NPHP module and its reduced dosage leads to a wide range of syndromic ciliopathies. 2022;31:2295
    https://doi.org/10.1093/hmg/ddac027
  77. Ondrej Bernatik, Petra Paclikova, Anna Kotrbova, Vitezslav Bryja, Lukas Cajanek. Primary Cilia Formation Does Not Rely on WNT/β-Catenin Signaling. Front. Cell Dev. Biol. 2021;9
    https://doi.org/10.3389/fcell.2021.623753
  78. Fatma Mansour, Felix J. Boivin, Iman B. Shaheed, Markus Schueler, Kai M. Schmidt-Ott. The Role of Centrosome Distal Appendage Proteins (DAPs) in Nephronophthisis and Ciliogenesis. IJMS 2021;22:12253
    https://doi.org/10.3390/ijms222212253
  79. Sofia Platova, Liudmila Poliushkevich, Milana Kulakova, Maksim Nesterenko, Viktor Starunov, Elena Novikova. Gotta Go Slow: Two Evolutionarily Distinct Annelids Retain a Common Hedgehog Pathway Composition, Outlining Its Pan-Bilaterian Core. IJMS 2022;23:14312
    https://doi.org/10.3390/ijms232214312
  80. João Gonçalves, Amit Sharma, Étienne Coyaud, Estelle M.N. Laurent, Brian Raught, Laurence Pelletier. LUZP1 and the tumor suppressor EPLIN modulate actin stability to restrict primary cilia formation. 2020;219
    https://doi.org/10.1083/jcb.201908132
  81. Miharisoa Rijatiana Ramanantsalama, Nicolas Landrein, Elina Casas, Bénédicte Salin, Corinne Blancard, Mélanie Bonhivers, Derrick R. Robinson, Denis Dacheux. TFK1, a basal body transition fibre protein that is essential for cytokinesis in Trypanosoma brucei . 2022;135
    https://doi.org/10.1242/jcs.259893
  82. Wolfgang Baehr, Christin Hanke-Gogokhia, Ali Sharif, Michelle Reed, Tiffanie Dahl, Jeanne M. Frederick, Guoxin Ying. Insights into photoreceptor ciliogenesis revealed by animal models. Progress in Retinal and Eye Research 2019;71:26
    https://doi.org/10.1016/j.preteyeres.2018.12.004
  83. Pierrick Le Borgne, Logan Greibill, Marine Hélène Laporte, Michel Lemullois, Khaled Bouhouche, Mebarek Temagoult, Olivier Rosnet, Maeva Le Guennec, Laurent Lignières, Guillaume Chevreux, France Koll, Virginie Hamel, Paul Guichard, Anne-Marie Tassin, Dagmar Wachten. The evolutionary conserved proteins CEP90, FOPNL, and OFD1 recruit centriolar distal appendage proteins to initiate their assembly. PLoS Biol 2022;20:e3001782
    https://doi.org/10.1371/journal.pbio.3001782
  84. Helena Soares, Bruno Carmona, Sofia Nolasco, Luís Viseu Melo, João Gonçalves. Cilia Distal Domain: Diversity in Evolutionarily Conserved Structures. Cells 2019;8:160
    https://doi.org/10.3390/cells8020160
  85. Huan Long, Kaiyao Huang. Transport of Ciliary Membrane Proteins. Front. Cell Dev. Biol. 2020;7
    https://doi.org/10.3389/fcell.2019.00381
  86. João Gonçalves. LUZP1: A new player in the actin-microtubule cross-talk. European Journal of Cell Biology 2022;101:151250
    https://doi.org/10.1016/j.ejcb.2022.151250
  87. Vrinda Sreekumar, Dominic P Norris. Cilia and development. Current Opinion in Genetics & Development 2019;56:15
    https://doi.org/10.1016/j.gde.2019.05.002
  88. Delphine Gogendeau, Michel Lemullois, Pierrick Le Borgne, Manon Castelli, Anne Aubusson-Fleury, Olivier Arnaiz, Jean Cohen, Christine Vesque, Sylvie Schneider-Maunoury, Khaled Bouhouche, France Koll, Anne-Marie Tassin, Dagmar Wachten. MKS-NPHP module proteins control ciliary shedding at the transition zone. PLoS Biol 2020;18:e3000640
    https://doi.org/10.1371/journal.pbio.3000640
  89. Tingting Lin, Yongyi Ma, Danni Zhou, Liwei Sun, Ke Chen, Yezhou Xiang, Keya Tong, Chaoli Jia, Kean Jiang, Dongyun Liu, Guoning Huang. Case Report: Preimplantation Genetic Testing for Meckel Syndrome Induced by Novel Compound Heterozygous Mutations of MKS1. Front. Genet. 2022;13
    https://doi.org/10.3389/fgene.2022.843931
  90. Veronica Persico, Giuliano Callaini, Maria Giovanna Riparbelli. The Microtubule-Depolymerizing Kinesin-13 Klp10A Is Enriched in the Transition Zone of the Ciliary Structures of Drosophila melanogaster. Front. Cell Dev. Biol. 2019;7
    https://doi.org/10.3389/fcell.2019.00173
  91. Abraham Andreu-Cervera, Martin Catala, Sylvie Schneider-Maunoury. Cilia, ciliopathies and hedgehog-related forebrain developmental disorders. Neurobiology of Disease 2021;150:105236
    https://doi.org/10.1016/j.nbd.2020.105236
  92. Xue Chen, Chen Zhao. Advances in Vision Research, Volume III. 2021.
    https://doi.org/10.1007/978-981-15-9184-6_16
  93. Elizabeth Michele Davies, Christina Anne Mitchell, Harald Alfred Stenmark. Phosphoinositides in New Spaces. Cold Spring Harb Perspect Biol 2023;15:a041406
    https://doi.org/10.1101/cshperspect.a041406
  94. Yamato Ishida, Koshi Tasaki, Yohei Katoh, Kazuhisa Nakayama, Gregory Pazour. Molecular basis underlying the ciliary defects caused by IFT52 variations found in skeletal ciliopathies. MBoC 2022;33
    https://doi.org/10.1091/mbc.E22-05-0188
  95. Dhivya Kumar, Richard E. Mains, Betty A. Eipper, Stephen M. King. Ciliary and cytoskeletal functions of an ancient monooxygenase essential for bioactive amidated peptide synthesis. Cell. Mol. Life Sci. 2019;76:2329
    https://doi.org/10.1007/s00018-019-03065-w
  96. Philip Stahl, Graça Raposo, Juan Wang, Maureen M. Barr. Cell–cell communication via ciliary extracellular vesicles: clues from model systems. 2018;62:205
    https://doi.org/10.1042/EBC20170085
  97. Francesca Finetti, Nagaja Capitani, Cosima T. Baldari. Emerging Roles of the Intraflagellar Transport System in the Orchestration of Cellular Degradation Pathways. Front. Cell Dev. Biol. 2019;7
    https://doi.org/10.3389/fcell.2019.00292
  98. Kelly M. Hennessey, Germain C. M. Alas, Ilse Rogiers, Renyu Li, Ethan A. Merritt, Alexander R. Paredez, Yixian Zheng. Nek8445, a protein kinase required for microtubule regulation and cytokinesis inGiardia lamblia. MBoC 2020;31:1611
    https://doi.org/10.1091/mbc.E19-07-0406
  99. Marta Lovera, Jens Lüders. The ciliary impact of nonciliary gene mutations. Trends in Cell Biology 2021;31:876
    https://doi.org/10.1016/j.tcb.2021.06.001
  100. Neha Quadri, Priyanka Upadhyai. Primary cilia in skeletal development and disease. Experimental Cell Research 2023;431:113751
    https://doi.org/10.1016/j.yexcr.2023.113751
  101. Huijie Zhao, Ziam Khan, Christopher J. Westlake. Ciliogenesis membrane dynamics and organization. Seminars in Cell & Developmental Biology 2023;133:20
    https://doi.org/10.1016/j.semcdb.2022.03.021
  102. T. Lynne Blasius, Daisuke Takao, Kristen J. Verhey, Hemant Khanna. NPHP proteins are binding partners of nucleoporins at the base of the primary cilium. PLoS ONE 2019;14:e0222924
    https://doi.org/10.1371/journal.pone.0222924
  103. Yuki Hamada, Yuta Tsurumi, Shohei Nozaki, Yohei Katoh, Kazuhisa Nakayama, Xueliang Zhu. Interaction of WDR60 intermediate chain with TCTEX1D2 light chain of the dynein-2 complex is crucial for ciliary protein trafficking. MBoC 2018;29:1628
    https://doi.org/10.1091/mbc.E18-03-0173
  104. Yi‐Ling Qiu, Li Wang, Min Huang, Min Lian, Fengbin Wang, Ying Gong, Xiong Ma, Chen‐Zhi Hao, Jing Zhang, Zhong‐Die Li, Qing‐He Xing, Muqing Cao, Jian‐She Wang. Association of novel TMEM67 variants with mild phenotypes of high gamma‐glutamyl transpeptidase cholestasis and congenital hepatic fibrosis. Journal Cellular Physiology 2022;237:2713
    https://doi.org/10.1002/jcp.30788
  105. Gabriela Edwards‐Faret, Arantxa Cebrián‐Silla, Emilio E. Méndez‐Olivos, Karina González‐Pinto, José Manuel García‐Verdugo, Juan Larraín. Cellular composition and organization of the spinal cord central canal during metamorphosis of the frog Xenopus laevis. J of Comparative Neurology 2018;526:1712
    https://doi.org/10.1002/cne.24441
  106. Aman George, Tiziana Cogliati, Brian P. Brooks. Genetics of syndromic ocular coloboma: CHARGE and COACH syndromes. Experimental Eye Research 2020;193:107940
    https://doi.org/10.1016/j.exer.2020.107940
  107. Eunbi Jo, Hyun-Jin Jang, Lei Shen, Kyeong Eun Yang, Min Su Jang, Yang Hoon Huh, Hwa-Seung Yoo, Junsoo Park, Ik Soon Jang, Soo Jung Park. Cordyceps militaris Exerts Anticancer Effect on Non–Small Cell Lung Cancer by Inhibiting Hedgehog Signaling via Suppression of TCTN3. Integr Cancer Ther 2020;19:153473542092375
    https://doi.org/10.1177/1534735420923756
  108. Quanlong Lu, Christopher J. Westlake. Cilia: From Mechanisms to Disease - Part B. 2020.
    https://doi.org/10.1016/bs.mcb.2023.02.001
  109. Miguel Barroso-Gil, Eric Olinger, John A. Sayer. Molecular genetics of renal ciliopathies. 2021;49:1205
    https://doi.org/10.1042/BST20200791
  110. Victor L Jensen, Nils J Lambacher, Chunmei Li, Swetha Mohan, Corey L Williams, Peter N Inglis, Bradley K Yoder, Oliver E Blacque, Michel R Leroux. Role for intraflagellar transport in building a functional transition zone. EMBO Reports 2018;19
    https://doi.org/10.15252/embr.201845862
  111. Zhuang Zhou, Yohei Katoh, Kazuhisa Nakayama, Gregory Pazour. CEP19–RABL2–IFT-B axis controls BBSome-mediated ciliary GPCR export. MBoC 2022;33
    https://doi.org/10.1091/mbc.E22-05-0161
  112. Sanne K. Verbakel, Ramon A.C. van Huet, Camiel J.F. Boon, Anneke I. den Hollander, Rob W.J. Collin, Caroline C.W. Klaver, Carel B. Hoyng, Ronald Roepman, B. Jeroen Klevering. Non-syndromic retinitis pigmentosa. Progress in Retinal and Eye Research 2018;66:157
    https://doi.org/10.1016/j.preteyeres.2018.03.005