Molecules and Cells

Cited by CrossRef (75)

  1. Holly Yu Chen, Emily Welby, Tiansen Li, Anand Swaroop, Meral Gunay-Aygun. Retinal disease in ciliopathies: Recent advances with a focus on stem cell-based therapies. TRD 2019;4:97
    https://doi.org/10.3233/TRD-190038
  2. Laura Vuolo, Nicola L. Stevenson, Aakash G. Mukhopadhyay, Anthony J. Roberts, David J. Stephens. Cytoplasmic dynein-2 at a glance. 2020;133
    https://doi.org/10.1242/jcs.240614
  3. Ke Ning, Emilie Song, Brent E. Sendayen, Philipp P. Prosseda, Kun‐Che Chang, Alireza Ghaffarieh, Jorge A. Alvarado, Biao Wang, Kathryn M. Haider, Nicolas F. Berbari, Yang Hu, Yang Sun. Defective INPP5E distribution in NPHP1‐related Senior–Loken syndrome. Mol Genet Genomic Med 2021;9
    https://doi.org/10.1002/mgg3.1566
  4. Abrar Choudhury, Neil M. Neumann, David R. Raleigh, Ursula E. Lang. Clinical Implications of Primary Cilia in Skin Cancer. Dermatol Ther (Heidelb) 2020;10:233
    https://doi.org/10.1007/s13555-020-00355-1
  5. Sarah E. Conduit, Bart Vanhaesebroeck. Phosphoinositide lipids in primary cilia biology. 2020;477:3541
    https://doi.org/10.1042/BCJ20200277
  6. Maria Giovanna Riparbelli, Veronica Persico, Romano Dallai, Giuliano Callaini. Centrioles and Ciliary Structures during Male Gametogenesis in Hexapoda: Discovery of New Models. Cells 2020;9:744
    https://doi.org/10.3390/cells9030744
  7. Elena A. May, Tommy J. Sroka, David U. Mick. Phosphorylation and Ubiquitylation Regulate Protein Trafficking, Signaling, and the Biogenesis of Primary Cilia. Front. Cell Dev. Biol. 2021;9
    https://doi.org/10.3389/fcell.2021.664279
  8. Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs. Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss. Cells 2020;9:931
    https://doi.org/10.3390/cells9040931
  9. Zhimao Wu, Nan Pang, Yingying Zhang, Huicheng Chen, Ying Peng, Jingyan Fu, Qing Wei, Renata Basto. CEP290 is essential for the initiation of ciliary transition zone assembly. PLoS Biol 2020;18:e3001034
    https://doi.org/10.1371/journal.pbio.3001034
  10. Mary Mirvis, Tim Stearns, W. James Nelson. Cilium structure, assembly, and disassembly regulated by the cytoskeleton. 2018;475:2329
    https://doi.org/10.1042/BCJ20170453
  11. Carolyn M. Ott. The Liver. 2018.
    https://doi.org/10.1002/9781119436812.ch5
  12. Shabarni Gupta, Justyna E. Ozimek-Kulik, Jacqueline Kathleen Phillips. Nephronophthisis-Pathobiology and Molecular Pathogenesis of a Rare Kidney Genetic Disease. Genes 2021;12:1762
    https://doi.org/10.3390/genes12111762
  13. Elena A. May, Marian Kalocsay, Inès Galtier D’Auriac, Patrick S. Schuster, Steven P. Gygi, Maxence V. Nachury, David U. Mick. Time-resolved proteomics profiling of the ciliary Hedgehog response. 2021;220
    https://doi.org/10.1083/jcb.202007207
  14. Cassandra L. Barnes, Himanshu Malhotra, Peter D. Calvert. Compartmentalization of Photoreceptor Sensory Cilia. Front. Cell Dev. Biol. 2021;9
    https://doi.org/10.3389/fcell.2021.636737
  15. Ciaran G. Morrison. Primary cilia and the DNA damage response: linking a cellular antenna and nuclear signals. 2021;49:829
    https://doi.org/10.1042/BST20200751
  16. Garrett A. Greenan, Ronald D. Vale, David A. Agard. Electron cryotomography of intact motile cilia defines the basal body to axoneme transition. 2020;219
    https://doi.org/10.1083/jcb.201907060
  17. Melissa A. Parisi, Meral Gunay-Aygun. The molecular genetics of Joubert syndrome and related ciliopathies: The challenges of genetic and phenotypic heterogeneity. TRD 2019;4:25
    https://doi.org/10.3233/TRD-190041
  18. Marco Gottardo, Veronica Persico, Giuliano Callaini, Maria Giovanna Riparbelli. The “transition zone” of the cilium-like regions in the Drosophila spermatocytes and the role of the C-tubule in axoneme assembly. Experimental Cell Research 2018;371:262
    https://doi.org/10.1016/j.yexcr.2018.08.020
  19. Jean-André Lapart, Amélie Billon, Jean-Luc Duteyrat, Joëlle Thomas, Bénédicte Durand. Role of DZIP1–CBY–FAM92 transition zone complex in the basal body to membrane attachment and ciliary budding. 2020;48:1067
    https://doi.org/10.1042/BST20191007
  20. Misato Okazaki, Takuya Kobayashi, Shuhei Chiba, Ryota Takei, Luxiaoxue Liang, Kazuhisa Nakayama, Yohei Katoh, Xueliang Zhu. Formation of the B9-domain protein complex MKS1–B9D2–B9D1 is essential as a diffusion barrier for ciliary membrane proteins. MBoC 2020;31:2259
    https://doi.org/10.1091/mbc.E20-03-0208
  21. Sidney T. Ley, Wissam A. AbouAlaiwi. Basic and Clinical Understanding of Microcirculation. 2020.
    https://doi.org/10.5772/intechopen.89680
  22. Melissa E. Truong, Sara Bilekova, Semil P. Choksi, Wan Li, Lukasz J. Bugaj, Ke Xu, Jeremy F. Reiter. Vertebrate cells differentially interpret ciliary and extraciliary cAMP. Cell 2021;184:2911
    https://doi.org/10.1016/j.cell.2021.04.002
  23. Jinghua Hu, Peter C. Harris. Regulation of polycystin expression, maturation and trafficking. Cellular Signalling 2020;72:109630
    https://doi.org/10.1016/j.cellsig.2020.109630
  24. Hantian Qiu, Sayaka Fujisawa, Shohei Nozaki, Yohei Katoh, Kazuhisa Nakayama. Interaction of INPP5E with ARL13B is essential for its ciliary membrane retention but dispensable for its ciliary entry. 2020
    https://doi.org/10.1242/bio.057653
  25. Anna Osinka, Martyna Poprzeczko, Magdalena M. Zielinska, Hanna Fabczak, Ewa Joachimiak, Dorota Wloga. Ciliary Proteins: Filling the Gaps. Recent Advances in Deciphering the Protein Composition of Motile Ciliary Complexes. Cells 2019;8:730
    https://doi.org/10.3390/cells8070730
  26. Melis Dilara Arslanhan, Dila Gulensoy, Elif Nur Firat-Karalar. A Proximity Mapping Journey into the Biology of the Mammalian Centrosome/Cilium Complex. Cells 2020;9:1390
    https://doi.org/10.3390/cells9061390
  27. Ondrej Bernatik, Petra Paclikova, Anna Kotrbova, Vitezslav Bryja, Lukas Cajanek. Primary Cilia Formation Does Not Rely on WNT/β-Catenin Signaling. Front. Cell Dev. Biol. 2021;9
    https://doi.org/10.3389/fcell.2021.623753
  28. Fatma Mansour, Felix J. Boivin, Iman B. Shaheed, Markus Schueler, Kai M. Schmidt-Ott. The Role of Centrosome Distal Appendage Proteins (DAPs) in Nephronophthisis and Ciliogenesis. IJMS 2021;22:12253
    https://doi.org/10.3390/ijms222212253
  29. João Gonçalves, Amit Sharma, Étienne Coyaud, Estelle M.N. Laurent, Brian Raught, Laurence Pelletier. LUZP1 and the tumor suppressor EPLIN modulate actin stability to restrict primary cilia formation. 2020;219
    https://doi.org/10.1083/jcb.201908132
  30. Wolfgang Baehr, Christin Hanke-Gogokhia, Ali Sharif, Michelle Reed, Tiffanie Dahl, Jeanne M. Frederick, Guoxin Ying. Insights into photoreceptor ciliogenesis revealed by animal models. Progress in Retinal and Eye Research 2019;71:26
    https://doi.org/10.1016/j.preteyeres.2018.12.004
  31. Antonia Wiegering, Ulrich Rüther, Christoph Gerhardt. The ciliary protein Rpgrip1l in development and disease. Developmental Biology 2018;442:60
    https://doi.org/10.1016/j.ydbio.2018.07.024
  32. Helena Soares, Bruno Carmona, Sofia Nolasco, Luís Viseu Melo, João Gonçalves. Cilia Distal Domain: Diversity in Evolutionarily Conserved Structures. Cells 2019;8:160
    https://doi.org/10.3390/cells8020160
  33. Deniz Conkar, Elif Nur Firat‐Karalar. Microtubule‐associated proteins and emerging links to primary cilium structure, assembly, maintenance, and disassembly. FEBS J. 2021;288:786
    https://doi.org/10.1111/febs.15473
  34. Huan Long, Kaiyao Huang. Transport of Ciliary Membrane Proteins. Front. Cell Dev. Biol. 2020;7
    https://doi.org/10.3389/fcell.2019.00381
  35. Wen-Ting Yang, Shi-Rong Hong, Kai He, Kun Ling, Kritika Shaiv, JingHua Hu, Yu-Chun Lin. The Emerging Roles of Axonemal Glutamylation in Regulation of Cilia Architecture and Functions. Front. Cell Dev. Biol. 2021;9
    https://doi.org/10.3389/fcell.2021.622302
  36. Fan Ye, Andrew R. Nager, Maxence V. Nachury. BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone. 2018;217:1847
    https://doi.org/10.1083/jcb.201709041
  37. Alind Gupta, Lacramioara Fabian, Julie A. Brill. Phosphatidylinositol 4,5-bisphosphate regulates cilium transition zone maturation in Drosophila melanogaster . 2018
    https://doi.org/10.1242/jcs.218297
  38. Westley Heydeck, Brian A. Bayless, Alexander J. Stemm-Wolf, Eileen T. O'Toole, Amy S. Fabritius, Courtney Ozzello, Marina Nguyen, Mark Winey. Tetrahymena Poc5 is a transient basal body component that is important for basal body maturation. 2020
    https://doi.org/10.1242/jcs.240838
  39. Wei Wang, Brittany M. Jack, Henry H. Wang, Matthew A. Kavanaugh, Robin L. Maser, Pamela V. Tran. Intraflagellar Transport Proteins as Regulators of Primary Cilia Length. Front. Cell Dev. Biol. 2021;9
    https://doi.org/10.3389/fcell.2021.661350
  40. Vrinda Sreekumar, Dominic P Norris. Cilia and development. Current Opinion in Genetics & Development 2019;56:15
    https://doi.org/10.1016/j.gde.2019.05.002
  41. Delphine Gogendeau, Michel Lemullois, Pierrick Le Borgne, Manon Castelli, Anne Aubusson-Fleury, Olivier Arnaiz, Jean Cohen, Christine Vesque, Sylvie Schneider-Maunoury, Khaled Bouhouche, France Koll, Anne-Marie Tassin, Dagmar Wachten. MKS-NPHP module proteins control ciliary shedding at the transition zone. PLoS Biol 2020;18:e3000640
    https://doi.org/10.1371/journal.pbio.3000640
  42. Veronica Persico, Giuliano Callaini, Maria Giovanna Riparbelli. The Microtubule-Depolymerizing Kinesin-13 Klp10A Is Enriched in the Transition Zone of the Ciliary Structures of Drosophila melanogaster. Front. Cell Dev. Biol. 2019;7
    https://doi.org/10.3389/fcell.2019.00173
  43. Abraham Andreu-Cervera, Martin Catala, Sylvie Schneider-Maunoury. Cilia, ciliopathies and hedgehog-related forebrain developmental disorders. Neurobiology of Disease 2021;150:105236
    https://doi.org/10.1016/j.nbd.2020.105236
  44. Xue Chen, Chen Zhao. Advances in Vision Research, Volume III. 2021.
    https://doi.org/10.1007/978-981-15-9184-6_16
  45. Madison Atkins, Jiří Týč, Shahaan Shafiq, Manu Ahmed, Eloïse Bertiaux, Artur Leonel De Castro Neto, Jack Sunter, Philippe Bastin, Samuel Dale Dean, Sue Vaughan. CEP164C regulates flagellum length in stable flagella. 2021;220
    https://doi.org/10.1083/jcb.202001160
  46. Laura Girardet, Céline Augière, Marie‐Pier Asselin, Clémence Belleannée. Primary cilia: biosensors of the male reproductive tract. Andrology 2019
    https://doi.org/10.1111/andr.12650
  47. Dhivya Kumar, Richard E. Mains, Betty A. Eipper, Stephen M. King. Ciliary and cytoskeletal functions of an ancient monooxygenase essential for bioactive amidated peptide synthesis. Cell. Mol. Life Sci. 2019;76:2329
    https://doi.org/10.1007/s00018-019-03065-w
  48. Philip Stahl, Graça Raposo, Juan Wang, Maureen M. Barr. Cell–cell communication via ciliary extracellular vesicles: clues from model systems. 2018;62:205
    https://doi.org/10.1042/EBC20170085
  49. Francesca Finetti, Nagaja Capitani, Cosima T. Baldari. Emerging Roles of the Intraflagellar Transport System in the Orchestration of Cellular Degradation Pathways. Front. Cell Dev. Biol. 2019;7
    https://doi.org/10.3389/fcell.2019.00292
  50. Kelly M. Hennessey, Germain C. M. Alas, Ilse Rogiers, Renyu Li, Ethan A. Merritt, Alexander R. Paredez, Yixian Zheng. Nek8445, a protein kinase required for microtubule regulation and cytokinesis in Giardia lamblia. MBoC 2020;31:1611
    https://doi.org/10.1091/mbc.E19-07-0406
  51. John Copeland. Actin-based regulation of ciliogenesis – The long and the short of it. Seminars in Cell & Developmental Biology 2020;102:132
    https://doi.org/10.1016/j.semcdb.2019.12.005
  52. Tiffany Yu, Miho Matsuda. Epb41l5 interacts with IQCB1 and regulates ciliary function in zebrafish embryos. 2020
    https://doi.org/10.1242/jcs.240648
  53. Hiroko Saito, Fumiko Matsukawa-Usami, Toshihiko Fujimori, Toshiya Kimura, Takahiro Ide, Takaki Yamamoto, Tatsuo Shibata, Kenta Onoue, Satoko Okayama, Shigenobu Yonemura, Kazuyo Misaki, Yurina Soba, Yasutaka Kakui, Masamitsu Sato, Mika Toya, Masatoshi Takeichi, Alpha Yap. Tracheal motile cilia in mice require CAMSAP3 for the formation of central microtubule pair and coordinated beating. MBoC 2021;32:ar12
    https://doi.org/10.1091/mbc.E21-06-0303
  54. Christiane Pleuger, Mari S Lehti, Jessica EM Dunleavy, Daniela Fietz, Moira K O’Bryan. Haploid male germ cells—the Grand Central Station of protein transport. 2020;26:474
    https://doi.org/10.1093/humupd/dmaa004
  55. Kazuhisa Nakayama, Yohei Katoh. Architecture of the IFT ciliary trafficking machinery and interplay between its components. Critical Reviews in Biochemistry and Molecular Biology 2020;55:179
    https://doi.org/10.1080/10409238.2020.1768206
  56. Marta Lovera, Jens Lüders. The ciliary impact of nonciliary gene mutations. Trends in Cell Biology 2021;31:876
    https://doi.org/10.1016/j.tcb.2021.06.001
  57. Timothy S McClintock, Naazneen Khan, Chao Xie, Jeffrey R Martens. Maturation of the Olfactory Sensory Neuron and Its Cilia. 2020;45:805
    https://doi.org/10.1093/chemse/bjaa070
  58. T. Lynne Blasius, Daisuke Takao, Kristen J. Verhey, Hemant Khanna. NPHP proteins are binding partners of nucleoporins at the base of the primary cilium. PLoS ONE 2019;14:e0222924
    https://doi.org/10.1371/journal.pone.0222924
  59. Jean-André Lapart, Marco Gottardo, Elisabeth Cortier, Jean-Luc Duteyrat, Céline Augière, Alain Mangé, Julie Jerber, Jérôme Solassol, Jay Gopalakrishnan, Joëlle Thomas, Bénédicte Durand. Dzip1 and Fam92 form a ciliary transition zone complex with cell type specific roles in Drosophila. 2019;8
    https://doi.org/10.7554/eLife.49307
  60. Khaled Bouhouche, Pierrick Le Borgne, Michel Lemullois, Anne-Marie Tassin. La paramécie, un organisme modèle pour étudier la ciliogenèse et les maladies ciliaires. Med Sci (Paris) 2021;37:632
    https://doi.org/10.1051/medsci/2021087
  61. Sarah E. Conduit, Elizabeth M. Davies, Alex J. Fulcher, Viola Oorschot, Christina A. Mitchell. Superresolution Microscopy Reveals Distinct Phosphoinositide Subdomains Within the Cilia Transition Zone. Front. Cell Dev. Biol. 2021;9
    https://doi.org/10.3389/fcell.2021.634649
  62. Yuki Hamada, Yuta Tsurumi, Shohei Nozaki, Yohei Katoh, Kazuhisa Nakayama, Xueliang Zhu. Interaction of WDR60 intermediate chain with TCTEX1D2 light chain of the dynein-2 complex is crucial for ciliary protein trafficking. MBoC 2018;29:1628
    https://doi.org/10.1091/mbc.E18-03-0173
  63. Nina Schweizer, Jens Lüders. From tip to toe – dressing centrioles in γTuRC. 2021;134
    https://doi.org/10.1242/jcs.258397
  64. Gabriela Edwards-Faret, Arantxa Cebrián-Silla, Emilio E. Méndez-Olivos, Karina González-Pinto, José Manuel García-Verdugo, Juan Larraín. Cellular composition and organization of the spinal cord central canal during metamorphosis of the frogXenopus laevis. J Comp Neurol 2018;526:1712
    https://doi.org/10.1002/cne.24441
  65. Maxence V. Nachury, David U. Mick. Establishing and regulating the composition of cilia for signal transduction. Nat Rev Mol Cell Biol 2019;20:389
    https://doi.org/10.1038/s41580-019-0116-4
  66. Aman George, Tiziana Cogliati, Brian P. Brooks. Genetics of syndromic ocular coloboma: CHARGE and COACH syndromes. Experimental Eye Research 2020;193:107940
    https://doi.org/10.1016/j.exer.2020.107940
  67. Eunbi Jo, Hyun-Jin Jang, Lei Shen, Kyeong Eun Yang, Min Su Jang, Yang Hoon Huh, Hwa-Seung Yoo, Junsoo Park, Ik Soon Jang, Soo Jung Park. Cordyceps militaris Exerts Anticancer Effect on Non–Small Cell Lung Cancer by Inhibiting Hedgehog Signaling via Suppression of TCTN3. Integr Cancer Ther 2020;19:153473542092375
    https://doi.org/10.1177/1534735420923756
  68. Yuta Tsurumi, Yuki Hamada, Yohei Katoh, Kazuhisa Nakayama, Xueliang Zhu. Interactions of the dynein-2 intermediate chain WDR34 with the light chains are required for ciliary retrograde protein trafficking. MBoC 2019;30:658
    https://doi.org/10.1091/mbc.E18-10-0678
  69. Miguel Barroso-Gil, Eric Olinger, John A. Sayer. Molecular genetics of renal ciliopathies. 2021;49:1205
    https://doi.org/10.1042/BST20200791
  70. Victor L Jensen, Nils J Lambacher, Chunmei Li, Swetha Mohan, Corey L Williams, Peter N Inglis, Bradley K Yoder, Oliver E Blacque, Michel R Leroux. Role for intraflagellar transport in building a functional transition zone. EMBO Rep 2018;19
    https://doi.org/10.15252/embr.201845862
  71. Huijie Zhao, Qingxia Chen, Fan Li, Lihong Cui, Lele Xie, Qiongping Huang, Xin Liang, Jun Zhou, Xiumin Yan, Xueliang Zhu. Fibrogranular materials function as organizers to ensure the fidelity of multiciliary assembly. Nat Commun 2021;12
    https://doi.org/10.1038/s41467-021-21506-8
  72. Sayaka Fujisawa, Hantian Qiu, Shohei Nozaki, Shuhei Chiba, Yohei Katoh, Kazuhisa Nakayama. ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane. 2021;10
    https://doi.org/10.1242/bio.058843
  73. Chao Xie, Jeffrey R Martens. Potential Therapeutic Targets for Olfactory Dysfunction in Ciliopathies Beyond Single-Gene Replacement. 2021;46
    https://doi.org/10.1093/chemse/bjab010
  74. Erum A. Hartung, Lisa M. Guay-Woodford. DZIP1L defines a new functional zip code for autosomal recessive PKD. Nat Rev Nephrol 2017;13:519
    https://doi.org/10.1038/nrneph.2017.102
  75. Sanne K. Verbakel, Ramon A.C. van Huet, Camiel J.F. Boon, Anneke I. den Hollander, Rob W.J. Collin, Caroline C.W. Klaver, Carel B. Hoyng, Ronald Roepman, B. Jeroen Klevering. Non-syndromic retinitis pigmentosa. Progress in Retinal and Eye Research 2018;66:157
    https://doi.org/10.1016/j.preteyeres.2018.03.005