Molecules and Cells

Cited by CrossRef (48)

  1. Tianyun Shen, Xinyuan Wang, Qingjia Xu, Lu Han, Shiyan Liu, Ting Huang, Hongyan Li, Lunzhi Dai, Huihui Li, kefeng lu. Function and Molecular Mechanism of N-Terminal Acetylation in Autophagy. SSRN Journal 2021
    https://doi.org/10.2139/ssrn.3802028
  2. Trevor Croft, Christol James Theoga Raj, Michelle Salemi, Brett S. Phinney, Su-Ju Lin. A functional link between NAD+ homeostasis and N-terminal protein acetylation in Saccharomyces cerevisiae. Journal of Biological Chemistry 2018;293:2927
    https://doi.org/10.1074/jbc.M117.807214
  3. Sarah M. Engle, Justin J. Crowder, Sheldon G. Watts, Christopher J. Indovina, Samuel Z. Coffey, Eric M. Rubenstein. Acetylation of N-terminus and two internal amino acids is dispensable for degradation of a protein that aberrantly engages the endoplasmic reticulum translocon. 2017;5:e3728
    https://doi.org/10.7717/peerj.3728
  4. Yujiao Liu, Chao Liu, Wen Dong, Wei Li. Physiological functions and clinical implications of the N-end rule pathway. Front. Med. 2016;10:258
    https://doi.org/10.1007/s11684-016-0458-7
  5. Xiaodi Gong, Yaqian Huang, Yan Liang, Yundong Yuan, Yuhao Liu, Tongwen Han, Shujia Li, Hengbin Gao, Bo Lv, Xiahe Huang, Eric Linster, Yingchun Wang, Markus Wirtz, Yonghong Wang. OsHYPK-mediated protein N-terminal acetylation coordinates plant development and abiotic stress responses in rice. Molecular Plant 2022;15:740
    https://doi.org/10.1016/j.molp.2022.03.001
  6. Yao Li, Yueling Zhao, Xiaojie Yan, Chen Ye, Sara Weirich, Bing Zhang, Xiaolu Wang, Lili Song, Chenhao Jiang, Albert Jeltsch, Cheng Dong, Wenyi Mi. CRL2ZER1/ZYG11B recognizes small N-terminal residues for degradation. Nat Commun 2022;13
    https://doi.org/10.1038/s41467-022-35169-6
  7. Kha The Nguyen, Chang-Seok Lee, Sang-Hyeon Mun, Nhung Thimy Truong, Sang Ki Park, Cheol-Sang Hwang. N-terminal acetylation and the N-end rule pathway control degradation of the lipid droplet protein PLIN2. Journal of Biological Chemistry 2019;294:379
    https://doi.org/10.1074/jbc.RA118.005556
  8. Arun Upadhyay. Structure of proteins: Evolution with unsolved mysteries. Progress in Biophysics and Molecular Biology 2019;149:160
    https://doi.org/10.1016/j.pbiomolbio.2019.04.007
  9. Brandon Wadas, Jimo Borjigin, Zheping Huang, Jang-Hyun Oh, Cheol-Sang Hwang, Alexander Varshavsky. Degradation of Serotonin N-Acetyltransferase, a Circadian Regulator, by the N-end Rule Pathway. Journal of Biological Chemistry 2016;291:17178
    https://doi.org/10.1074/jbc.M116.734640
  10. Kha The Nguyen, Sang-Hyeon Mun, Chang-Seok Lee, Cheol-Sang Hwang. Control of protein degradation by N-terminal acetylation and the N-end rule pathway. Exp Mol Med 2018;50:1
    https://doi.org/10.1038/s12276-018-0097-y
  11. Federica Donnarumma, Valeria Tucci, Concetta Ambrosino, Lucia Altucci, Vincenzo Carafa. NAA60 (HAT4): the newly discovered bi-functional Golgi member of the acetyltransferase family. Clin Epigenet 2022;14
    https://doi.org/10.1186/s13148-022-01402-8
  12. Daniel J. Gibbs, Mark Bailey, Hannah M. Tedds, Michael J. Holdsworth. From start to finish: amino‐terminal protein modifications as degradation signals in plants. New Phytologist 2016;211:1188
    https://doi.org/10.1111/nph.14105
  13. Tao WANG, Jiaxin LI, Qian-Hua SHEN. Regulation of NLR stability in plant immunity. Front. Agr. Sci. Eng. 2019;6:97
    https://doi.org/10.15302/J-FASE-2018248
  14. Cheng Dong, Heng Zhang, Li Li, Wolfram Tempel, Peter Loppnau, Jinrong Min. Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway. Nat Chem Biol 2018;14:466
    https://doi.org/10.1038/s41589-018-0036-1
  15. Mohamed A. Eldeeb, Luana C.A. Leitao, Richard P. Fahlman. Emerging branches of the N-end rule pathways are revealing the sequence complexities of N-termini dependent protein degradation. Biochem. Cell Biol. 2018;96:289
    https://doi.org/10.1139/bcb-2017-0274
  16. David A. Dougan. Pro(moting) the Turnover of Gluconeogenic Enzymes by a New Branch of the N-end Rule Pathway. Trends in Biochemical Sciences 2017;42:330
    https://doi.org/10.1016/j.tibs.2017.03.006
  17. Nico Dissmeyer, Susana Rivas, Emmanuelle Graciet. Life and death of proteins after protease cleavage: protein degradation by the N‐end rule pathway. New Phytologist 2018;218:929
    https://doi.org/10.1111/nph.14619
  18. Xu Wang, Marlène Davanture, Michel Zivy, Christophe Bailly, Eiji Nambara, Françoise Corbineau. Label-Free Quantitative Proteomics Reveal the Involvement of PRT6 in Arabidopsis thaliana Seed Responsiveness to Ethylene. IJMS 2022;23:9352
    https://doi.org/10.3390/ijms23169352
  19. Argho Aninda Paul, Natalia A. Szulc, Adrian Kobiela, Sara J. Brown, Wojciech Pokrzywa, Danuta Gutowska-Owsiak. In silico analysis of the profilaggrin sequence indicates alterations in the stability, degradation route, and intracellular protein fate in filaggrin null mutation carriers. Front. Mol. Biosci. 2023;10
    https://doi.org/10.3389/fmolb.2023.1105678
  20. Brandon Wadas, Konstantin I. Piatkov, Christopher S. Brower, Alexander Varshavsky. Analyzing N-terminal Arginylation through the Use of Peptide Arrays and Degradation Assays. Journal of Biological Chemistry 2016;291:20976
    https://doi.org/10.1074/jbc.M116.747956
  21. Françoise Corbineau. Oxygen, a key signalling factor in the control of seed germination and dormancy. Seed Sci. Res. 2022;32:126
    https://doi.org/10.1017/S096025852200006X
  22. Ngee Kiat Chua, Hudson W. Coates, Andrew J. Brown. Squalene monooxygenase: a journey to the heart of cholesterol synthesis. Progress in Lipid Research 2020;79:101033
    https://doi.org/10.1016/j.plipres.2020.101033
  23. Kelly A. Hyndman, Chin-Rang Yang, Hyun Jun Jung, Ezigbobiara N. Umejiego, Chung-Ling Chou, Mark A. Knepper. Proteomic determination of the lysine acetylome and phosphoproteome in the rat native inner medullary collecting duct. Physiological Genomics 2018;50:669
    https://doi.org/10.1152/physiolgenomics.00029.2018
  24. Hongtao Zhang, Lucy Gannon, Peter D. Jones, Chelsea A. Rundle, Kirsty L. Hassall, Daniel J. Gibbs, Michael J. Holdsworth, Frederica L. Theodoulou. Genetic interactions between ABA signalling and the Arg/N-end rule pathway during Arabidopsis seedling establishment. Sci Rep 2018;8
    https://doi.org/10.1038/s41598-018-33630-5
  25. Chen Liu, Panagiotis N. Moschou. Phenotypic novelty by CRISPR in plants. Developmental Biology 2018;435:170
    https://doi.org/10.1016/j.ydbio.2018.01.015
  26. Fabien Piguet, Hadjer Ouldali, Manuela Pastoriza-Gallego, Philippe Manivet, Juan Pelta, Abdelghani Oukhaled. Identification of single amino acid differences in uniformly charged homopolymeric peptides with aerolysin nanopore. Nat Commun 2018;9
    https://doi.org/10.1038/s41467-018-03418-2
  27. . Co and Post‐Translational Modifications of Therapeutic Antibodies and Proteins. 2018.
    https://doi.org/10.1002/9781119053354.ch2
  28. Tianyun Shen, Lan Jiang, Xinyuan Wang, Qingjia Xu, Lu Han, Shiyan Liu, Ting Huang, Hongyan Li, Lunzhi Dai, Huihui Li, Kefeng Lu. Function and molecular mechanism of N-terminal acetylation in autophagy. Cell Reports 2021;37:109937
    https://doi.org/10.1016/j.celrep.2021.109937
  29. Alexandra G. Knorr, Christian Schmidt, Petr Tesina, Otto Berninghausen, Thomas Becker, Birgitta Beatrix, Roland Beckmann. Ribosome–NatA architecture reveals that rRNA expansion segments coordinate N-terminal acetylation. Nat Struct Mol Biol 2019;26:35
    https://doi.org/10.1038/s41594-018-0165-y
  30. Kha The Nguyen, Jeong-Mok Kim, Sang-Eun Park, Cheol-Sang Hwang. N-terminal methionine excision of proteins creates tertiary destabilizing N-degrons of the Arg/N-end rule pathway. Journal of Biological Chemistry 2019;294:4464
    https://doi.org/10.1074/jbc.RA118.006913
  31. Jihye Yang, Yoontae Lee, Cheol-Sang Hwang. The ubiquitin–proteasome system links NADPH metabolism to ferroptosis. Trends in Cell Biology 2023
    https://doi.org/10.1016/j.tcb.2023.07.003
  32. Mohamed A. Eldeeb, Richard P. Fahlman, Mohamed A. Ragheb, Mansoore Esmaili. Does N‐Terminal Protein Acetylation Lead to Protein Degradation?. BioEssays 2019;41
    https://doi.org/10.1002/bies.201800167
  33. Zhentao Sheng, Wei Du, Norbert Perrimon. NatB regulates Rb mutant cell death and tumor growth by modulating EGFR/MAPK signaling through the N-end rule pathways. PLoS Genet 2020;16:e1008863
    https://doi.org/10.1371/journal.pgen.1008863
  34. Sun Myung Kim, Eunyoung Ha, Jinyoung Kim, Chiheum Cho, So-Jin Shin, Ji Hae Seo. NAA10 as a New Prognostic Marker for Cancer Progression. IJMS 2020;21:8010
    https://doi.org/10.3390/ijms21218010
  35. Anna P. Loboda, Surinder M. Soond, Mauro Piacentini, Nickolai A. Barlev. Lysine-specific post-translational modifications of proteins in the life cycle of viruses. Cell Cycle 2019;18:1995
    https://doi.org/10.1080/15384101.2019.1639305
  36. Rasmus Ree, Sylvia Varland, Thomas Arnesen. Spotlight on protein N-terminal acetylation. Exp Mol Med 2018;50:1
    https://doi.org/10.1038/s12276-018-0116-z
  37. Olga I. Kechko, Irina Yu. Petrushanko, Christopher S. Brower, Alexei A. Adzhubei, Alexey A. Moskalev, Konstantin I. Piatkov, Vladimir A. Mitkevich, Alexander A. Makarov. Beta-amyloid induces apoptosis of neuronal cells by inhibition of the Arg/N-end rule pathway proteolytic activity. Aging 2019;11:6134
    https://doi.org/10.18632/aging.102177
  38. Joon Sung Park, Jae-Young Lee, Yen Thi Kim Nguyen, Nae-Won Kang, Eun Kyung Oh, Dong Man Jang, Hyun-Jung Kim, Dae-Duk Kim, Byung Woo Han. Structural Analyses on the Deamidation of N-Terminal Asn in the Human N-Degron Pathway. Biomolecules 2020;10:163
    https://doi.org/10.3390/biom10010163
  39. Yung-Wei Lin, Yu-Ching Wen, Chih-Ying Chu, Min-Che Tung, Yi-Chieh Yang, Kuo-Tai Hua, Ke-Fan Pan, Michael Hsiao, Wei-Jiunn Lee, Ming-Hsien Chien. Stabilization of ADAM9 by N-α-acetyltransferase 10 protein contributes to promoting progression of androgen-independent prostate cancer. Cell Death Dis 2020;11
    https://doi.org/10.1038/s41419-020-02786-2
  40. Dawafuti Sherpa, Jakub Chrustowicz, Brenda A. Schulman. How the ends signal the end: Regulation by E3 ubiquitin ligases recognizing protein termini. Molecular Cell 2022;82:1424
    https://doi.org/10.1016/j.molcel.2022.02.004
  41. Richard T. Timms, Itay Koren. Tying up loose ends: the N-degron and C-degron pathways of protein degradation. 2020;48:1557
    https://doi.org/10.1042/BST20191094
  42. Alexandra Miricescu, Kevin Goslin, Emmanuelle Graciet. Ubiquitylation in plants: signaling hub for the integration of environmental signals. 2018;69:4511
    https://doi.org/10.1093/jxb/ery165
  43. Jasmin Elurbide, Beatriz Carte, Joana Guedes, Rafael Aldabe. NatB Catalytic Subunit Depletion Disrupts DNA Replication Initiation Leading to Senescence in MEFs. IJMS 2023;24:8724
    https://doi.org/10.3390/ijms24108724
  44. Nico Dissmeyer, Emmanuelle Graciet, Michael J. Holdsworth, Daniel J. Gibbs. N-term 2017: Proteostasis via the N-terminus. Trends in Biochemical Sciences 2019;44:293
    https://doi.org/10.1016/j.tibs.2017.11.006
  45. Dong-Young Seo, Dasom Kim, Kha The Nguyen, Junsoo Oh, Jung-Shin Lee, Cheol-Sang Hwang. N-Terminally arginylated ubiquitin is attached to histone H2A by RING1B E3 ligase in human cells. Biochemical and Biophysical Research Communications 2023;666:186
    https://doi.org/10.1016/j.bbrc.2023.02.022
  46. Douwe de Boer, Alexander S. Streng, William P. T. M. van Doorn, Wim H. M. Vroemen, Otto Bekers, Will K. W. H. Wodzig, Alma M. A. Mingels. Translational Urinomics. 2023.
    https://doi.org/10.1007/978-3-030-63908-2_4
  47. Xiaojie Yan, Yao Li, Guobin Wang, Zhili Zhou, Guangyong Song, Qiqi Feng, Yueling Zhao, Wenyi Mi, Zhenyi Ma, Cheng Dong. Molecular basis for recognition of Gly/N-degrons by CRL2ZYG11B and CRL2ZER1. Molecular Cell 2021;81:3262
    https://doi.org/10.1016/j.molcel.2021.06.010
  48. Kha The Nguyen, Shinyeong Ju, Sang-Yoon Kim, Chang-Seok Lee, Cheolju Lee, Cheol-Sang Hwang. N-Terminal Modifications of Ubiquitin via Methionine Excision, Deamination, and Arginylation Expand the Ubiquitin Code. Mol.Cells 2022;45:158
    https://doi.org/10.14348/molcells.2022.2027