Molecules and Cells

Cited by CrossRef (56)

  1. Bo Li, Zhipeng Liao, Yingxi Mo, Weilin Zhao, Xiaohui Zhou, Xiling Xiao, Wanmeng Cui, Guofei Feng, Suhua Zhong, Yushan Liang, Chunping Du, Guangwu Huang, Ping Li, Xue Xiao, Xiaoying Zhou, Rensheng Wang, Zhe Zhang. Inactivation of 3-hydroxybutyrate dehydrogenase type 2 promotes proliferation and metastasis of nasopharyngeal carcinoma by iron retention. Br J Cancer 2020;122:102
    https://doi.org/10.1038/s41416-019-0638-8
  2. Chao Zhao, Hu Zhang, Jingjing Zhou, Qiwei Liu, Qiang Lu, Ying Zhang, Xiaojin Yu, Shizhi Wang, Ran Liu, Yuepu Pu, Lihong Yin. Metabolomic transition trajectory and potential mechanisms of N-nitrosomethylbenzylamine induced esophageal squamous cell carcinoma in rats. Ecotoxicology and Environmental Safety 2022;244:114071
    https://doi.org/10.1016/j.ecoenv.2022.114071
  3. Lishuang Ding, Xuezheng Liang. Ras related GTP binding D promotes aerobic glycolysis of hepatocellular carcinoma. Annals of Hepatology 2021;23:100307
    https://doi.org/10.1016/j.aohep.2021.100307
  4. Yihui Ruan, Xin Fang, Tingyue Guo, Yiting Liu, Yu Hu, Xuening Wang, Yuxin Hu, Lanyue Gao, Yongfang Li, Jingbo Pi, Yuanyuan Xu. Metabolic reprogramming in the arsenic carcinogenesis. Ecotoxicology and Environmental Safety 2022;229:113098
    https://doi.org/10.1016/j.ecoenv.2021.113098
  5. Antonietta Rosella Farina, Lucia Cappabianca, Pierdomenico Ruggeri, Luciana Gneo, Cristina Pellegrini, Maria-Concetta Fargnoli, Andrew Reay Mackay. The oncogenic neurotrophin receptor tropomyosin-related kinase variant, TrkAIII. J Exp Clin Cancer Res 2018;37
    https://doi.org/10.1186/s13046-018-0786-3
  6. Praveen Deepak. Handbook of Research on Natural Products and Their Bioactive Compounds as Cancer Therapeutics. 2018.
    https://doi.org/10.4018/978-1-7998-9258-8.ch015
  7. Andrew C. Little, Arvis Sulovari, Karamatullah Danyal, David E. Heppner, David J. Seward, Albert van der Vliet. Paradoxical roles of dual oxidases in cancer biology. Free Radical Biology and Medicine 2017;110:117
    https://doi.org/10.1016/j.freeradbiomed.2017.05.024
  8. Juan Cai, Zhiqiang Chen, Jinguo Wang, Junfeng Wang, Xianjun Chen, Linhu Liang, Min Huang, Zhengrong Zhang, Xueliang Zuo. circHECTD1 facilitates glutaminolysis to promote gastric cancer progression by targeting miR-1256 and activating β-catenin/c-Myc signaling. Cell Death Dis 2019;10
    https://doi.org/10.1038/s41419-019-1814-8
  9. Angela Poff, Andrew P. Koutnik, Kathleen M. Egan, Solmaz Sahebjam, Dominic D’Agostino, Nagi B. Kumar. Targeting the Warburg effect for cancer treatment: Ketogenic diets for management of glioma. Seminars in Cancer Biology 2019;56:135
    https://doi.org/10.1016/j.semcancer.2017.12.011
  10. Deri Morgan, Kiersten L. Berggren, Colby D. Spiess, Hannah M. Smith, Ajay Tejwani, Scott J. Weir, Christopher E. Lominska, Sufi M. Thomas, Gregory N. Gan. Mitogen‐activated protein kinase‐activated protein kinase‐2 (MK2) and its role in cell survival, inflammatory signaling, and migration in promoting cancer. Molecular Carcinogenesis 2022;61:173
    https://doi.org/10.1002/mc.23348
  11. Jiajun Huang, Ze Long, Wanjun Lin, Xiaolin Liao, Ying Xie, Liang Liu, Wenzhe Ma. Integrative omics analysis of p53-dependent regulation of metabolism. FEBS Lett 2018;592:380
    https://doi.org/10.1002/1873-3468.12968
  12. Yufan Wu, Zhuxian Wang, Qunqun Du, Zhaoming Zhu, Tingting Chen, Yaqi Xue, Yuan Wang, Quanfu Zeng, Chunyan Shen, Cuiping Jiang, Li Liu, Hongxia Zhu, Qiang Liu, Jianping Chen. Pharmacological Effects and Underlying Mechanisms of Licorice-Derived Flavonoids. Evidence-Based Complementary and Alternative Medicine 2022;2022:1
    https://doi.org/10.1155/2022/9523071
  13. Hitendra S. Solanki, Niraj Babu, Ankit P. Jain, Mohd Younis Bhat, Vinuth N. Puttamallesh, Jayshree Advani, Remya Raja, Kiran K. Mangalaparthi, Mahesh M. Kumar, T.S.Keshava Prasad, Premendu Prakash Mathur, David Sidransky, Harsha Gowda, Aditi Chatterjee. Cigarette smoke induces mitochondrial metabolic reprogramming in lung cells. Mitochondrion 2018;40:58
    https://doi.org/10.1016/j.mito.2017.10.002
  14. Antonietta Rosella Farina, Lucia Cappabianca, Luciana Gneo, Pierdomenico Ruggeri, Andrew Reay Mackay. TrkAIII signals endoplasmic reticulum stress to the mitochondria in neuroblastoma cells, resulting in glycolytic metabolic adaptation. Oncotarget 2018;9:8368
    https://doi.org/10.18632/oncotarget.23618
  15. Yongyan Sun, Zhenhua Shi, Yahong Wang, Chao Tang, Yanyan Liao, Chuanjun Yang, Peng Cai. Coupling of oxidative stress responses to tricarboxylic acid cycle and prostaglandin E2 alterations in Caenorhabditis elegans under extremely low-frequency electromagnetic field. International Journal of Radiation Biology 2018;94:1159
    https://doi.org/10.1080/09553002.2019.1524943
  16. Wenqi Luo, Liting Qin, Bo Li, Zhipeng Liao, Jiezhen Liang, Xiling Xiao, Xue Xiao, Yingxi Mo, Guangwu Huang, Zhe Zhang, Xiaoying Zhou, Ping Li. Inactivation of HMGCL promotes proliferation and metastasis of nasopharyngeal carcinoma by suppressing oxidative stress. Sci Rep 2017;7
    https://doi.org/10.1038/s41598-017-11025-2
  17. Yong Liao. Cancer metabolism as we know it today. Genes & Diseases 2017;4:4
    https://doi.org/10.1016/j.gendis.2017.02.001
  18. Renata Ramalho, Martin Rao, Chao Zhang, Chiara Agrati, Giuseppe Ippolito, Fu-Sheng Wang, Alimuddin Zumla, Markus Maeurer. Immunometabolism: new insights and lessons from antigen-directed cellular immune responses. Semin Immunopathol 2020;42:279
    https://doi.org/10.1007/s00281-020-00798-w
  19. Zhiming Xiao, Shaojun Liu, Feiyan Ai, Xiong Chen, Xiayu Li, Rui Liu, Weiguo Ren, Xuemei Zhang, Peng Shu, Decai Zhang. SDHB downregulation facilitates the proliferation and invasion of colorectal cancer through AMPK functions excluding those involved in the modulation of aerobic glycolysis. Exp Ther Med 2017
    https://doi.org/10.3892/etm.2017.5482
  20. Kaiqiang Guo, Yin Cao, Zan Li, Xiaoxiao Zhou, Rong Ding, Kejing Chen, Yan Liu, Yingkun Qiu, Zhen Wu, Meijuan Fang. Glycine metabolomic changes induced by anticancer agents in A549 cells. Amino Acids 2020;52:793
    https://doi.org/10.1007/s00726-020-02853-0
  21. Liuyu Xu, Hongyun Li, Longchao Wu, Shiming Huang. YBX1 promotes tumor growth by elevating glycolysis in human bladder cancer. Oncotarget 2017;8:65946
    https://doi.org/10.18632/oncotarget.19583
  22. Jing Zhang, Xiang Li, Leaf Huang. Anticancer activities of phytoconstituents and their liposomal targeting strategies against tumor cells and the microenvironment. Advanced Drug Delivery Reviews 2020;154-155:245
    https://doi.org/10.1016/j.addr.2020.05.006
  23. Yunliang Lu, Xiaohui Zhou, Weilin Zhao, Zhipeng Liao, Bo Li, Peipei Han, Yanping Yang, Xuemin Zhong, Yingxi Mo, Ping Li, Guangwu Huang, Xue Xiao, Zhe Zhang, Xiaoying Zhou. Epigenetic Inactivation of Acetyl-CoA Acetyltransferase 1 Promotes the Proliferation and Metastasis in Nasopharyngeal Carcinoma by Blocking Ketogenesis. Front. Oncol. 2021;11
    https://doi.org/10.3389/fonc.2021.667673
  24. Ângela R. Guerra, Ana F. Paulino, Maria M. Castro, Helena Oliveira, Maria F. Duarte, Iola F. Duarte. Triple Negative Breast Cancer and Breast Epithelial Cells Differentially Reprogram Glucose and Lipid Metabolism upon Treatment with Triterpenic Acids. Biomolecules 2020;10:1163
    https://doi.org/10.3390/biom10081163
  25. Jiacheng Cao, Xing Zhang, Penghui Xu, Haixiao Wang, Sen Wang, Lu Zhang, Zheng Li, Li Xie, Guangli Sun, Yiwen Xia, Jialun Lv, Jing Yang, Zekuan Xu. Circular RNA circLMO7 acts as a microRNA-30a-3p sponge to promote gastric cancer progression via the WNT2/β-catenin pathway. J Exp Clin Cancer Res 2021;40
    https://doi.org/10.1186/s13046-020-01791-9
  26. Kyoung Song, Hun Seok Lee, Lina Jia, Chaithanya Chelakkot, Nirmal Rajasekaran, Young Kee Shin. SMAD4 Controls Cancer Cell Metabolism by Regulating Methylmalonic Aciduria Cobalamin Deficiency (cbl) B Type. Mol.Cells 2022;45:413
    https://doi.org/10.14348/molcells.2022.0067
  27. Shibo Wei, Qing Fan, Liang Yang, Xiaodong Zhang, Yingbo Ma, Zhihong Zong, Xiangdong Hua, Dongming Su, Hongzhi Sun, Hangyu Li, Zhen Liu. Promotion of glycolysis by HOTAIR through GLUT1 upregulation via mTOR signaling. 2017;38:1902
    https://doi.org/10.3892/or.2017.5840
  28. Varinder Kaur, Manish Kumar, Ajay Kumar, Kamaldeep Kaur, Varinderpal Singh Dhillon, Satwinderjeet Kaur. Pharmacotherapeutic potential of phytochemicals: Implications in cancer chemoprevention and future perspectives. Biomedicine & Pharmacotherapy 2018;97:564
    https://doi.org/10.1016/j.biopha.2017.10.124
  29. Monica Neagu, Carolina Constantin, Iulia Dana Popescu, Donato Zipeto, George Tzanakakis, Dragana Nikitovic, Concettina Fenga, Constantine A. Stratakis, Demetrios A. Spandidos, Aristidis M. Tsatsakis. Inflammation and Metabolism in Cancer Cell—Mitochondria Key Player. Front. Oncol. 2019;9
    https://doi.org/10.3389/fonc.2019.00348
  30. Fei Chen, Jianing Chen, Linbin Yang, Jiang Liu, Xiaoqian Zhang, Yin Zhang, Qingqiang Tu, Dong Yin, Dechen Lin, Ping-Pui Wong, Di Huang, Yue Xing, Jinghua Zhao, Mengfeng Li, Qiang Liu, Fengxi Su, Shicheng Su, Erwei Song. Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells. Nat Cell Biol 2019;21:498
    https://doi.org/10.1038/s41556-019-0299-0
  31. Xiaoting Pan, Wenhao Chen, Mengjun Nie, Yuanjie Liu, Zuopeng Xiao, Ying Zhang, Wei Zhang, Xi Zou. A Serum Metabolomic Study Reveals Changes in Metabolites During the Treatment of Lung Cancer-Bearing Mice with Anlotinib. CMAR 2021;Volume 13:6055
    https://doi.org/10.2147/CMAR.S300897
  32. John A. Hanover, Weiping Chen, Michelle R. Bond. O-GlcNAc in cancer: An Oncometabolism-fueled vicious cycle. J Bioenerg Biomembr 2018;50:155
    https://doi.org/10.1007/s10863-018-9751-2
  33. Areej Abu Rmaileh, Balakrishnan Solaimuthu, Mayur Tanna, Anees Khatib, Michal Ben Yosef, Arata Hayashi, Michal Lichtenstein, Yoav D. Shaul. Large-Scale Differential Gene Expression Transcriptomic Analysis Identifies a Metabolic Signature Shared by All Cancer Cells. Biomolecules 2020;10:701
    https://doi.org/10.3390/biom10050701
  34. Fengju Chen, Yiqun Zhang, Dominick Bossé, Aly-Khan A. Lalani, A. Ari Hakimi, James J. Hsieh, Toni K. Choueiri, Don L. Gibbons, Michael Ittmann, Chad J. Creighton. Pan-urologic cancer genomic subtypes that transcend tissue of origin. Nat Commun 2017;8
    https://doi.org/10.1038/s41467-017-00289-x
  35. Loganathan Chandramani Priya Dharshini, Rajan Radha Rasmi, Chinnadurai Kathirvelan, Kalavathi Murugan Kumar, K. M. Saradhadevi, Kunnathur Murugesan Sakthivel. Regulatory Components of Oxidative Stress and Inflammation and Their Complex Interplay in Carcinogenesis. Appl Biochem Biotechnol 2022
    https://doi.org/10.1007/s12010-022-04266-z
  36. Yi-Ta Hsieh, Yi-Fen Chen, Shu-Chun Lin, Kuo-Wei Chang, Wan-Chun Li. Targeting Cellular Metabolism Modulates Head and Neck Oncogenesis. IJMS 2019;20:3960
    https://doi.org/10.3390/ijms20163960
  37. Alison Colquhoun. Cell biology-metabolic crosstalk in glioma. The International Journal of Biochemistry & Cell Biology 2017;89:171
    https://doi.org/10.1016/j.biocel.2017.05.022
  38. José M. Matés, José A. Campos-Sandoval, Juan de los Santos-Jiménez, Juan A. Segura, Francisco J. Alonso, Javier Márquez. Metabolic Reprogramming of Cancer by Chemicals that Target Glutaminase Isoenzymes. CMC 2020;27:5317
    https://doi.org/10.2174/0929867326666190416165004
  39. Kun Fan, Shulong Zhang, Xiaojian Ni, Sheng Shen, Jiwen Wang, Wentao Sun, Tao Suo, Han Liu, Xiaoling Ni, Houbao Liu. KRAS G12D mutation eliminates reactive oxygen species through the Nrf2/CSE/H <sub>2</sub>S axis and contributes to pancreatic cancer growth. ABBS 2022
    https://doi.org/10.3724/abbs.2022173
  40. Shirisha Jonnalagadda, Sravan K. Jonnalagadda, Conor T. Ronayne, Grady L. Nelson, Lucas N. Solano, Jon Rumbley, Jon Holy, Venkatram R. Mereddy, Lester R. Drewes. Novel N,N-dialkyl cyanocinnamic acids as monocarboxylate transporter 1 and 4 inhibitors. Oncotarget 2019;10:2355
    https://doi.org/10.18632/oncotarget.26760
  41. Shaojun Liu, Zhiming Xiao, Feiyan Ai, Fen Liu, Xiong Chen, Ke Cao, Weiguo Ren, Xuemei Zhang, Peng Shu, Decai Zhang. miR-142-5p promotes development of colorectal cancer through targeting SDHB and facilitating generation of aerobic glycolysis. Biomedicine & Pharmacotherapy 2017;92:1119
    https://doi.org/10.1016/j.biopha.2017.05.134
  42. Ana Cavaco, Maryam Rezaei, Stephan Niland, Johannes A. Eble. Collateral Damage Intended—Cancer-Associated Fibroblasts and Vasculature Are Potential Targets in Cancer Therapy. IJMS 2017;18:2355
    https://doi.org/10.3390/ijms18112355
  43. York Kamenisch, Irina Ivanova, Konstantin Drexler, Mark Berneburg. UVA, metabolism and melanoma: UVA makes melanoma hungry for metastasis. Exp Dermatol 2018;27:941
    https://doi.org/10.1111/exd.13561
  44. Sonia Missiroli, Ilaria Genovese, Mariasole Perrone, Bianca Vezzani, Veronica A. M. Vitto, Carlotta Giorgi. The Role of Mitochondria in Inflammation: From Cancer to Neurodegenerative Disorders. JCM 2020;9:740
    https://doi.org/10.3390/jcm9030740
  45. Mardiana Lee, Marina Katerelos, Kurt Gleich, Sandra Galic, Bruce E. Kemp, Peter F. Mount, David A. Power. Phosphorylation of Acetyl-CoA Carboxylase by AMPK Reduces Renal Fibrosis and Is Essential for the Anti-Fibrotic Effect of Metformin. JASN 2018;29:2326
    https://doi.org/10.1681/ASN.2018010050
  46. Yang Chen, Ya-ran Wu, Hong-ying Yang, Xin-zhe Li, Meng-meng Jie, Chang-jiang Hu, Yu-yun Wu, Shi-ming Yang, Ying-bin Yang. Prolyl isomerase Pin1: a promoter of cancer and a target for therapy. Cell Death Dis 2018;9
    https://doi.org/10.1038/s41419-018-0844-y
  47. Dalia M. Kopustinskiene, Valdas Jakstas, Arunas Savickas, Jurga Bernatoniene. Flavonoids as Anticancer Agents. Nutrients 2020;12:457
    https://doi.org/10.3390/nu12020457
  48. Haseeb Zubair, Shafquat Azim, Aamir Ahmad, Mohammad Khan, Girijesh Patel, Seema Singh, Ajay Singh. Cancer Chemoprevention by Phytochemicals: Nature’s Healing Touch. Molecules 2017;22:395
    https://doi.org/10.3390/molecules22030395
  49. Niina M. Santio, Päivi J. Koskinen. PIM kinases: From survival factors to regulators of cell motility. The International Journal of Biochemistry & Cell Biology 2017;93:74
    https://doi.org/10.1016/j.biocel.2017.10.016
  50. Shu-Jie Zhao, Yi-Fei Shen, Qing Li, Yun-Jie He, Yun-Kun Zhang, Li-Peng Hu, Yu-Qing Jiang, Nan-Wei Xu, Yu-Ji Wang, Jun Li, Ya-Hui Wang, Fei Liu, Rong Zhang, Guo-Yong Yin, Jin-Hai Tang, Dong Zhou, Zhi-Gang Zhang. SLIT2/ROBO1 axis contributes to the Warburg effect in osteosarcoma through activation of SRC/ERK/c-MYC/PFKFB2 pathway. Cell Death Dis 2018;9
    https://doi.org/10.1038/s41419-018-0419-y
  51. Anees Khatib, Balakrishnan Solaimuthu, Michal Ben Yosef, Areej Abu Rmaileh, Mayur Tanna, Gidi Oren, Michal Schlesinger Frisch, Jonathan H. Axelrod, Michal Lichtenstein, Yoav D. Shaul. The glutathione peroxidase 8 (GPX8)/IL-6/STAT3 axis is essential in maintaining an aggressive breast cancer phenotype. Proc. Natl. Acad. Sci. U.S.A. 2020;117:21420
    https://doi.org/10.1073/pnas.2010275117
  52. C Zhang, X Zong, Y Han. Effect of butein and glucose on oxidative stress and p38 activation marker in non-small cell lung cancer cell. Hum Exp Toxicol 2019;38:1155
    https://doi.org/10.1177/0960327119851250
  53. Sonu Benny, Rohan Mishra, Maneesha K Manojkumar, T.P. Aneesh. From Warburg effect to Reverse Warburg effect; the new horizons of anti-cancer therapy. Medical Hypotheses 2020;144:110216
    https://doi.org/10.1016/j.mehy.2020.110216
  54. Wei Qu, Shuping Qiao, Ling Liu, Ying Chen, Chen Peng, Yayi Hou, Zhen Xu, Mingming Lv, Tingting Wang. Dectin3 protects against hepatocellular carcinoma by regulating glycolysis of macrophages. International Immunopharmacology 2022;113:109384
    https://doi.org/10.1016/j.intimp.2022.109384
  55. Peter Vaupel, Heinz Schmidberger, Arnulf Mayer. The Warburg effect: essential part of metabolic reprogramming and central contributor to cancer progression. International Journal of Radiation Biology 2019;95:912
    https://doi.org/10.1080/09553002.2019.1589653
  56. Ronan Talty, Kelly Olino. Metabolism of Innate Immune Cells in Cancer. Cancers 2021;13:904
    https://doi.org/10.3390/cancers13040904