Molecules and Cells

Cited by CrossRef (43)

  1. Ashley J. Dittmar, Allison A. Drozda, Ira J. Blader, William J. Sullivan. Drug Repurposing Screening Identifies Novel Compounds That Effectively Inhibit Toxoplasma gondii Growth. mSphere 2016;1
    https://doi.org/10.1128/mSphere.00042-15
  2. OMER ERDOGAN, GULEN MELIKE DEMIRBOLAT, OZGE CEVIK. Raloxifene-loaded and aptamer-bonded exosomes induce autophagic and apoptotic death in HeLa cells by enhancing the lysosomotropic effect. 2023;47:1051
    https://doi.org/10.32604/biocell.2023.028129
  3. JuOae Chang, Jihoon Kim, Wonsik Lee. Raloxifene prevents intracellular invasion of pathogenic bacteria through modulation of cell metabolic pathways. 2022;77:1617
    https://doi.org/10.1093/jac/dkac069
  4. Arindam Bhattacharjee, Mohammad Hasanain, Manoj Kathuria, Akhilesh Singh, Dipak Datta, Jayanta Sarkar, Kalyan Mitra. Ormeloxifene-induced unfolded protein response contributes to autophagy-associated apoptosis via disruption of Akt/mTOR and activation of JNK. Sci Rep 2018;8
    https://doi.org/10.1038/s41598-018-20541-8
  5. Darko P. Ašanin, Sanja Skaro Bogojevic, Franc Perdih, Tina P. Andrejević, Dusan Milivojevic, Ivana Aleksic, Jasmina Nikodinovic-Runic, Biljana Đ. Glišić, Iztok Turel, Miloš I. Djuran. Structural Characterization, Antimicrobial Activity and BSA/DNA Binding Affinity of New Silver(I) Complexes with Thianthrene and 1,8-Naphthyridine. Molecules 2021;26:1871
    https://doi.org/10.3390/molecules26071871
  6. Hendrik Folkerts, Susan Hilgendorf, Edo Vellenga, Edwin Bremer, Valerie R. Wiersma. The multifaceted role of autophagy in cancer and the microenvironment. Medicinal Research Reviews 2019;39:517
    https://doi.org/10.1002/med.21531
  7. Nan Gao, Yang Yang, Siqi Liu, Chunyang Fang, Xiujing Dou, Licong Zhang, Anshan Shan. Gut-Derived Metabolites from Dietary Tryptophan Supplementation Quench Intestinal Inflammation through the AMPK-SIRT1-Autophagy Pathway. J. Agric. Food Chem. 2022;70:16080
    https://doi.org/10.1021/acs.jafc.2c05381
  8. Usama A. Fahmy, Shaimaa M. Badr-Eldin, Hibah M. Aldawsari, Nabil A. Alhakamy, Osama A. A. Ahmed, Mohamed F. Radwan, Basma G. Eid, Shaban R. M. Sayed, Gamal A. El Sherbiny, Walaa Abualsunun. Potentiality of raloxifene loaded melittin functionalized lipidic nanovesicles against pancreatic cancer cells. Drug Delivery 2022;29:1863
    https://doi.org/10.1080/10717544.2022.2072544
  9. Anaelle da Costa, Christèle Picoli, Franck Mouthon, Mathieu Charvériat. Automated Assays to Identify Modulators of Transcription Factor EB Translocation and Autophagy. ASSAY and Drug Development Technologies 2022;20:67
    https://doi.org/10.1089/adt.2021.119
  10. Eunhye Lee, Aree Moon. Identification of Biomarkers for Breast Cancer Using Databases. J Cancer Prev 2016;21:235
    https://doi.org/10.15430/JCP.2016.21.4.235
  11. Liang Ouyang, Lan Zhang, Jie Liu, Leilei Fu, Dahong Yao, Yuqian Zhao, Shouyue Zhang, Guan Wang, Gu He, Bo Liu. Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer. J. Med. Chem. 2017;60:9990
    https://doi.org/10.1021/acs.jmedchem.7b00275
  12. Mikhail M. Savitski, Nico Zinn, Maria Faelth-Savitski, Daniel Poeckel, Stephan Gade, Isabelle Becher, Marcel Muelbaier, Anne J. Wagner, Katrin Strohmer, Thilo Werner, Stephanie Melchert, Massimo Petretich, Anna Rutkowska, Johanna Vappiani, Holger Franken, Michael Steidel, Gavain M. Sweetman, Omer Gilan, Enid Y.N. Lam, Mark A. Dawson, Rab K. Prinjha, Paola Grandi, Giovanna Bergamini, Marcus Bantscheff. Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis. Cell 2018;173:260
    https://doi.org/10.1016/j.cell.2018.02.030
  13. Nisheeth C. Desai, Dharmpalsinh J. Jadeja, Vijay M. Khedkar. Design, synthesis, antimicrobial activity and in silico molecular docking studies of some sulfur containing pyrazole-pyridine hybrids. Phosphorus, Sulfur, and Silicon and the Related Elements 2022;197:1226
    https://doi.org/10.1080/10426507.2022.2085271
  14. Laetitia Lesire, Ludovic Chaput, Paulina Cruz De Casas, Fanny Rousseau, Catherine Piveteau, Julie Dumont, David Pointu, Benoît Déprez, Florence Leroux. High-Throughput Image-Based Aggresome Quantification. SLAS Discovery 2020;25:783
    https://doi.org/10.1177/2472555220919708
  15. Ruth Ruiz Esparza-Garrido, María Eugenia Torres-Márquez, Rubí Viedma-Rodríguez, Ana Claudia Velázquez-Wong, Fabio Salamanca-Gómez, Haydeé Rosas-Vargas, Miguel Ángel Velázquez-Flores. Breast cancer cell line MDA-MB-231 miRNA profile expression after BIK interference: BIK involvement in autophagy. Tumor Biol. 2016;37:6749
    https://doi.org/10.1007/s13277-015-4494-8
  16. Zhimin Fu, Bin Luo, Mingpeng Li, Bin Peng, Zheng Wang. Effects of Raloxifene on the Proliferation and Apoptosis of Human Aortic Valve Interstitial Cells. BioMed Research International 2016;2016:1
    https://doi.org/10.1155/2016/5473204
  17. Chung S. Yang, Hong Wang, Vi Dan, Savanna San Filippo. Cancer Chemoprevention: What Have we Learned?. Curr Pharmacol Rep 2017;3:409
    https://doi.org/10.1007/s40495-017-0108-z
  18. Shaimaa M. Badr-Eldin, Hibah M. Aldawsari, Osama A.A. Ahmed, Nabil A. Alhakamy, Thikryat Neamatallah, Solomon Z. Okbazghi, Usama A. Fahmy. Optimized semisolid self-nanoemulsifying system based on glyceryl behenate: A potential nanoplatform for enhancing antitumor activity of raloxifene hydrochloride in MCF-7 human breast cancer cells. International Journal of Pharmaceutics 2021;600:120493
    https://doi.org/10.1016/j.ijpharm.2021.120493
  19. Anju Sharma, Jarriaun Streets, Priyanka Bhatt, Pranav Patel, Vijaykumar Sutariya, Sheeba Varghese Gupta. Formulation and Characterization of Raloxifene Nanostructured Lipid Carriers for Permeability and Uptake Enhancement Applications. ASSAY and Drug Development Technologies 2022;20:164
    https://doi.org/10.1089/adt.2022.004
  20. Hibah M. Aldawsari, Osama A. A. Ahmed, Nabil A. Alhakamy, Thikryat Neamatallah, Usama A. Fahmy, Shaimaa M. Badr-Eldin. Lipidic Nano-Sized Emulsomes Potentiates the Cytotoxic and Apoptotic Effects of Raloxifene Hydrochloride in MCF-7 Human Breast Cancer Cells: Factorial Analysis and In Vitro Anti-Tumor Activity Assessment. Pharmaceutics 2021;13:783
    https://doi.org/10.3390/pharmaceutics13060783
  21. Jeremy Johnson, Piotr Rychahou, Vitaliy M. Sviripa, Heidi L. Weiss, Chunming Liu, David S. Watt, B. Mark Evers, Jingwu Xie. Induction of AMPK activation by N,N’-diarylurea FND-4b decreases growth and increases apoptosis in triple negative and estrogen-receptor positive breast cancers. PLoS ONE 2019;14:e0209392
    https://doi.org/10.1371/journal.pone.0209392
  22. Caimei He, Hai Tang, Zijian Mei, Nichujie Li, Zhi Zeng, Kwame Oteng Darko, Yulong Yin, Chien-An Andy Hu, Xiaoping Yang. Human interstitial cellular model in therapeutics of heart valve calcification. Amino Acids 2017;49:1981
    https://doi.org/10.1007/s00726-017-2432-3
  23. Ravikanth Nanduri, Rashi Kalra, Ella Bhagyaraj, Anuja P. Chacko, Nancy Ahuja, Drishti Tiwari, Sumit Kumar, Monika Jain, Raman Parkesh, Pawan Gupta. AutophagySMDB: a curated database of small molecules that modulate protein targets regulating autophagy. Autophagy 2019;15:1280
    https://doi.org/10.1080/15548627.2019.1571717
  24. Xiao Cui, Zhao Li, Jie Gao, Peng-Ji Gao, Yan-bing Ni, Ji-Ye Zhu. Elevated CXCL1 increases hepatocellular carcinoma aggressiveness and is inhibited by miRNA-200a. Oncotarget 2016;7:65052
    https://doi.org/10.18632/oncotarget.11350
  25. Shelly Pathania, Raj Kumar Narang, Ravindra K. Rawal. Role of sulphur-heterocycles in medicinal chemistry: An update. European Journal of Medicinal Chemistry 2019;180:486
    https://doi.org/10.1016/j.ejmech.2019.07.043
  26. Waleska Kerllen Martins, Maryana do Nascimento da Silva, Kiran Pandey, Ikuko Maejima, Ercília Ramalho, Vania Claudia Olivon, Susana Nogueira Diniz, Daniel Grasso. Autophagy-targeted therapy to modulate age-related diseases: Success, pitfalls, and new directions. Current Research in Pharmacology and Drug Discovery 2021;2:100033
    https://doi.org/10.1016/j.crphar.2021.100033
  27. Balwinder Kaur, Gurdeep Singh, Vikas Sharma, Iqubal Singh. Sulphur Containing Heterocyclic Compounds as Anticancer Agents. ACAMC 2023;23:869
    https://doi.org/10.2174/1871520623666221221143918
  28. Ling Zou, Minru Liao, Yongqi Zhen, Shiou Zhu, Xiya Chen, Jin Zhang, Yue Hao, Bo Liu. Autophagy and beyond: Unraveling the complexity of UNC-51-like kinase 1 (ULK1) from biological functions to therapeutic implications. Acta Pharmaceutica Sinica B 2022;12:3743
    https://doi.org/10.1016/j.apsb.2022.06.004
  29. Van Thi-Hong Tran, Duc-Vinh Pham, Dong-Young Choi, Pil-Hoon Park. Mitophagy Induction and Aryl Hydrocarbon Receptor-Mediated Redox Signaling Contribute to the Suppression of Breast Cancer Cell Growth by Taloxifene via Regulation of Inflammasomes Activation. Antioxidants & Redox Signaling 2022;37:1030
    https://doi.org/10.1089/ars.2021.0192
  30. Naresh Kumar, Nidhi Goel. Heterocyclic Compounds: Importance in Anticancer Drug Discovery. ACAMC 2022;22:3196
    https://doi.org/10.2174/1871520622666220404082648
  31. Shuo Wang, Kai Wang, Huaiquan Wang, Jiankui Han, Hukui Sun. Autophagy is essential for flavopiridol-induced cytotoxicity against MCF-7 breast cancer cells. 2017;16:9715
    https://doi.org/10.3892/mmr.2017.7815
  32. Hsin-Wu Lai, James Cheng-Chung Wei, Hung-Chang Hung, Chun-Che Lin. Adenine Inhibits the Growth of Colon Cancer Cells via AMP-Activated Protein Kinase Mediated Autophagy. Evidence-Based Complementary and Alternative Medicine 2019;2019:1
    https://doi.org/10.1155/2019/9151070
  33. Xiangyu Liu, Kangjian Sun, Handong Wang, Yuyuan Dai. Inhibition of Autophagy by Chloroquine Enhances the Antitumor Efficacy of Sorafenib in Glioblastoma. Cell Mol Neurobiol 2016;36:1197
    https://doi.org/10.1007/s10571-015-0318-z
  34. Marcos Antonio Custódio Neto da Silva, Jonas Henrique Costa, Taícia Pacheco-Fill, Ana Lúcia Tasca Gois Ruiz, Flávia Castello Branco Vidal, Kátia Regina Assunção Borges, Sulayne Janaina Araújo Guimarães, Ana Paula Silva de Azevedo-Santos, Kaio Eduardo Buglio, Mary Ann Foglio, Maria do Carmo Lacerda Barbosa, Maria do Desterro Soares Brandão Nascimento, João Ernesto de Carvalho. Açai (Euterpe oleracea Mart.) Seed Extract Induces ROS Production and Cell Death in MCF-7 Breast Cancer Cell Line. Molecules 2021;26:3546
    https://doi.org/10.3390/molecules26123546
  35. Ming Gao, Changying Li, Ming Xu, Yun Liu, Sijin Liu. LncRNA UCA1 attenuates autophagy-dependent cell death through blocking autophagic flux under arsenic stress. Toxicology Letters 2018;284:195
    https://doi.org/10.1016/j.toxlet.2017.12.009
  36. Nabil A. Alhakamy, Usama A. Fahmy, Osama A. A. Ahmed, Xin Yi. Vitamin E TPGS based transferosomes augmented TAT as a promising delivery system for improved transdermal delivery of raloxifene. PLoS ONE 2019;14:e0226639
    https://doi.org/10.1371/journal.pone.0226639
  37. Jana Deitersen, Lena Berning, Fabian Stuhldreier, Sara Ceccacci, David Schlütermann, Annabelle Friedrich, Wenxian Wu, Yadong Sun, Philip Böhler, Niklas Berleth, María José Mendiburo, Sabine Seggewiß, Ruchika Anand, Andreas S. Reichert, Maria Chiara Monti, Peter Proksch, Björn Stork. High-throughput screening for natural compound-based autophagy modulators reveals novel chemotherapeutic mode of action for arzanol. Cell Death Dis 2021;12
    https://doi.org/10.1038/s41419-021-03830-5
  38. Tian Mao, Ouyang Liang. Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. 2021.
    https://doi.org/10.1016/B978-0-12-805420-8.00012-3
  39. Yumiko Watanabe-Yasuoka, Ayako Gotou, Shigeomi Shimizu, Toshihiro Sashihara. Lactiplantibacillus plantarum OLL2712 Induces Autophagy via MYD88 and Strengthens Tight Junction Integrity to Promote the Barrier Function in Intestinal Epithelial Cells. Nutrients 2023;15:2655
    https://doi.org/10.3390/nu15122655
  40. Jin Xiang, Xiang Liu, Jing Ren, Kun Chen, Hong-lu Wang, Yu-yang Miao, Miao-miao Qi. How does estrogen work on autophagy?. Autophagy 2019;15:197
    https://doi.org/10.1080/15548627.2018.1520549
  41. Zhi Xu, Chun-Ming Huang, Zhe Shao, Xiao-Ping Zhao, Meng Wang, Ting-Lin Yan, Xiao-Cheng Zhou, Er-Hui Jiang, Ke Liu, Zheng-Jun Shang. Autophagy Induced by Areca Nut Extract Contributes to Decreasing Cisplatin Toxicity in Oral Squamous Cell Carcinoma Cells: Roles of Reactive Oxygen Species/AMPK Signaling. IJMS 2017;18:524
    https://doi.org/10.3390/ijms18030524
  42. Liang Ji, Le Li, Fengzhi Qu, Guangquan Zhang, Yongwei Wang, Xuewei Bai, Shangha Pan, Dongbo Xue, Gang Wang, Bei Sun. Hydrogen sulphide exacerbates acute pancreatitis by over‐activating autophagy viaAMPK/mTOR pathway. J Cellular Molecular Medi 2016;20:2349
    https://doi.org/10.1111/jcmm.12928
  43. Yinnan Chen, Yanmin Zhang. Application of the CRISPR/Cas9 System to Drug Resistance in Breast Cancer. Advanced Science 2018;5
    https://doi.org/10.1002/advs.201700964