Molecules and Cells

Research Article 31 January 2020

Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity

The red-crowned crane (Grus japonensis) is an endangered, large-bodied crane native to East Asia. It is a traditional symbol of longevity and its long lifespan has been confirmed both in captivity and in the wild. Lifespan in birds is known to be positively correlated with body size and negatively correlated with metabolic rate, though the genetic mechanisms for the red-crowned crane’s long lifespan have not previously been investigated. Using whole genome sequencing and co ...
Research Article 31 January 2020

CrABCA2 Facilitates Triacylglycerol Accumulation in Chlamydomonas reinhardtii under Nitrogen Starvation

The microalga Chlamydomonas reinhardtii accumulates triacylglycerols (TAGs) in lipid droplets under stress conditions, such as nitrogen starvation. TAG biosynthesis occurs mainly at the endoplasmic reticulum (ER) and requires fatty acid (FA) substrates supplied from chloroplasts. How FAs are transferred from chloroplast to ER in microalgae was unknown. We previously reported that an Arabidopsis thaliana ATP-binding cassette (ABC) transporter, AtABCA9, facilit ...
Research Article 31 January 2020

The Tumor Suppressor, p53, Negatively Regulates Non-Canonical NF-κB Signaling through miRNAInduced Silencing of NF-κB?Inducing Kinase

NF-κB signaling through both canonical and non-canonical pathways plays a central role in immune responses and inflammation. NF-κB?inducing kinase (NIK) stabilization is a key step in activation of the non-canonical pathway and its dysregulation implicated in various hematologic malignancies. The tumor suppressor, p53, is an established cellular gatekeeper of proliferation. Abnormalities of the TP53 gene have been detected in more than half of all human cancers. While the n ...
Minireview 31 January 2020

Mitophagy and Innate Immunity in Infection

Mitochondria have several quality control mechanisms by which they maintain cellular homeostasis and ensure that the molecular machinery is protected from stress. Mitophagy, selective autophagy of mitochondria, promotes mitochondrial quality control by inducing clearance of damaged mitochondria via the autophagic machinery. Accumulating evidence suggests that mitophagy is modulated by various microbial components in an attempt to affect the innate immune response to infection. In addition, mi ...

Mol. Cells 2020; 43(1): 1~95

Minireviews

Lung Cancer Staging and Associated Genetic and Epigenetic Events

Dohun Kim, You-Soub Lee, Duk-Hwan Kim, and Suk-Chul Bae

Mol. Cells 2020; 43(1): 1-9 https://doi.org/10.14348/molcells.2020.2246

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Mitophagy and Innate Immunity in Infection

Dong-Hyung Cho, Jin Kyung Kim, and Eun-Kyeong Jo

Mol. Cells 2020; 43(1): 10-22 https://doi.org/10.14348/molcells.2020.2329

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Research Articles

The Tumor Suppressor, p53, Negatively Regulates Non-Canonical NF-κB Signaling through miRNAInduced Silencing of NF-κB?Inducing Kinase

Hanbit Jang, Seulki Park, Jaehoon Kim, Jong Hwan Kim, Seon-Young Kim, Sayeon Cho, Sung Goo Park, Byoung Chul Park, Sunhong Kim, and Jeong-Hoon Kim

Mol. Cells 2020; 43(1): 23-33 https://doi.org/10.14348/molcells.2019.0239

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Rev-erbα Negatively Regulates Osteoclast and Osteoblast Differentiation through p38 MAPK Signaling Pathway

Kabsun Kim, Jung Ha Kim, Inyoung Kim, Semun Seong, and Nacksung Kim

Mol. Cells 2020; 43(1): 34-47 https://doi.org/10.14348/molcells.2019.0232

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CrABCA2 Facilitates Triacylglycerol Accumulation in Chlamydomonas reinhardtii under Nitrogen Starvation

Sunghoon Jang, Fantao Kong, Jihyeon Lee, Bae Young Choi, Pengfei Wang, Peng Gao, Takashi Yamano, Hideya Fukuzawa, Byung-Ho Kang, and Youngsook Lee

Mol. Cells 2020; 43(1): 48-57 https://doi.org/10.14348/molcells.2019.0262

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Fat Mass and Obesity-Associated (FTO) Stimulates Osteogenic Differentiation of C3H10T1/2 Cells by Inducing Mild Endoplasmic Reticulum Stress via a Positive Feedback Loop with p-AMPK

Hyo-Eun Son, Hyeon-Young Min, Eun-Jung Kim, and Won-Gu Jang

Mol. Cells 2020; 43(1): 58-65 https://doi.org/10.14348/molcells.2019.0136

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Mitochondrial Ca²⁺ Uptake Relieves Palmitate-Induced Cytosolic Ca²⁺ Overload in MIN6 Cells

Luong Dai Ly, Dat Da Ly, Nhung Thi Nguyen, Ji-Hee Kim, Heesuk Yoo, Jongkyeong Chung, Myung-Shik Lee, Seung-Kuy Cha, and Kyu-Sang Park

Mol. Cells 2020; 43(1): 66-75 https://doi.org/10.14348/molcells.2019.0223

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march5 Governs the Convergence and Extension Movement for Organization of the Telencephalon and Diencephalon in Zebrafish Embryos

Jangham Jung, Issac Choi, Hyunju Ro, Tae-Lin Huh, Joonho Choe, and Myungchull Rhee

Mol. Cells 2020; 43(1): 76-85 https://doi.org/10.14348/molcells.2019.0210

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Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity

HyeJin Lee, Jungeun Kim, Jessica A. Weber, Oksung Chung, Yun Sung Cho, Sungwoong Jho, JeHoon Jun, Hak-Min Kim, Jeongheui Lim, Jae-Pil Choi, Sungwon Jeon, Asta Blazyte, Jeremy S. Edwards, Woon Kee Paek, and Jong Bhak

Mol. Cells 2020; 43(1): 86-95 https://doi.org/10.14348/molcells.2019.0190

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Current Issue

31 January 2020
Volume 43,
Number 1,
pp. 1~95

dRAGging Amino Acid-mTORC1 Signaling by SH3BP4

Young-Mi Kim, and Do-Hyung Kim*
Received September 19, 2012; Accepted December 4, 2012.

Olfactory Carbon Dioxide Detection by Insects and Other Animals

Walton Jones
Received January 30, 2013; Accepted February 2, 2013.

Broad Activity against Porcine Bacterial Pathogens Displayed by Two Insect Antimicrobial Peptides Moricin and Cecropin B

Han Hu, Chunmei Wang, Xiaozhen Guo, Wentao Li, Yang Wang, and Qigai He
Received May 4, 2012; Accepted November 20, 2012.

A MAP Kinase Pathway Is Implicated in the Pseudohyphal Induction by Hydrogen Peroxide in Candica albicans

Kavitha Srinivasa, Jihyun Kim, Subog Yee, Wankee Kim*, and Wonja Choi*

Activation of Rice nicotianamine synthase 2 (OsNAS2) Enhances Iron Availability for Biofortification

Sichul Lee, You-Sun Kim, Un Sil Jeon, Yoon-Keun Kim, Jan K. Schjoerring, and Gynheung An*

Rhythmic Oscillation of Histone Acetylation and Methylation at the Arabidopsis Central Clock Loci

Hae-Ryong Song, and Yoo-Sun Noh*

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