• Research Article  30 September 2020

    Crystal Structure of β-Carbonic Anhydrase CafA from the Fungal Pathogen Aspergillus fumigatus

    The β-class of carbonic anhydrases (β-CAs) are zinc metalloenzymes widely distributed in the fungal kingdom that play essential roles in growth, survival, differentiation, and virulence by catalyzing the reversible interconversion of carbon dioxide (CO2) and bicarbonate (HCO3). Herein, we report the biochemical and crystallographic characterization of the β-CA CafA from the fungal pathogen Aspergillus fumigatus, the main causative agent of invasive a ...

  • Research Article  30 September 2020

    Insight into Structural Aspects of Histidine 284 of Daphnia magna Arginine Kinase

    Arginine kinase (AK), a bioenergy-related enzyme, is distributed widely in invertebrates. The role of highly conserved histidines in AKs is still unascertained. In this study, the highly conserved histidine 284 (H284) in AK of Daphnia magna (DmAK) was replaced with alanine to elucidate the role of H284. We examined the alteration of catalytic activity and structural changes of H284A in DmAK. The catalytic activity of H284A was reduced dramatically compared to that in wild ty ...

  • Minireview  30 September 2020

    WNT Signaling in Lung Repair and Regeneration

    The lung has a vital function in gas exchange between the blood and the external atmosphere. It also has a critical role in the immune defense against external pathogens and environmental factors. While the lung is classified as a relatively quiescent organ with little homeostatic turnover, it shows robust regenerative capacity in response to injury, mediated by the resident stem/progenitor cells. During regeneration, regionally distinct epithelial cell populations with specific functions are ge ...

  • Minireview  30 September 2020

    Classifying the Linkage between Adipose Tissue Inflammation and Tumor Growth through Cancer-Associated Adipocytes

    Recently, tumor microenvironment (TME) and its stromal constituents have provided profound insights into understanding alterations in tumor behavior. After each identification regarding the unique roles of TME compartments, non-malignant stromal cells are found to provide a sufficient tumorigenic niche for cancer cells. Of these TME constituents, adipocytes represent a dynamic population mediating endocrine effects to facilitate the crosstalk between cancer cells and distant organs, as well as t ...


Mol. Cells 2020; 43(9): 763~840
Minireviews
Classifying the Linkage between Adipose Tissue Inflammation and Tumor Growth through Cancer-Associated Adipocytes
Yae Chan Song , Seung Eon Lee , Young Jin , Hyun Woo Park , Kyung-Hee Chun , and Han-Woong Lee
Mol. Cells 2020; 43(9): 763-773  https://doi.org/10.14348/molcells.2020.0118 PDF PubMed Google Scholar Search
WNT Signaling in Lung Repair and Regeneration
Ahmed A. Raslan and Jeong Kyo Yoon
Mol. Cells 2020; 43(9): 774-783  https://doi.org/10.14348/molcells.2020.0059 PDF PubMed Google Scholar Search
Research Articles
Insight into Structural Aspects of Histidine 284 of Daphnia magna Arginine Kinase
Zhili Rao , So Young Kim , Xiaotong Li , Da Som Kim , Yong Ju Kim , and Jung Hee Park
Mol. Cells 2020; 43(9): 784-792  https://doi.org/10.14348/molcells.2020.0136 PDF PubMed Supplementary File(s) Google Scholar Search
MicroRNA 449c Mediates the Generation of Monocytic Myeloid-Derived Suppressor Cells by Targeting STAT6
Xiaoqing Han , Tao Luan , Yingying Sun , Wenyi Yan , Dake Wang , and Xianlu Zeng
Mol. Cells 2020; 43(9): 793-803  https://doi.org/10.14348/molcells.2020.2307 PDF PubMed Supplementary File(s) Google Scholar Search
EMPAS: Electron Microscopy Screening for Endogenous Protein Architectures
Gijeong Kim , Seongmin Jang , Eunhye Lee , and Ji-Joon Song
Mol. Cells 2020; 43(9): 804-812  https://doi.org/10.14348/molcells.2020.0163 PDF PubMed Supplementary File(s) Google Scholar Search
Peroxiredoxin 3 Has Important Roles on Arsenic Trioxide Induced Apoptosis in Human Acute Promyelocytic Leukemia Cell Line via Hyperoxidation of Mitochondrial Specific Reactive Oxygen Species
Yeung-Chul Mun , Jee Young Ahn , Eun Sun Yoo , Kyoung Eun Lee , Eun Mi Nam , Jungwon Huh , Hyun Ae Woo , Sue Goo Rhee , and Chu Myong Seong
Mol. Cells 2020; 43(9): 813-820  https://doi.org/10.14348/molcells.2020.2234 PDF PubMed Google Scholar Search
C9orf72-Associated Arginine-Rich Dipeptide Repeat Proteins Reduce the Number of Golgi Outposts and Dendritic Branches in Drosophila Neurons
Jeong Hyang Park , Chang Geon Chung , Jinsoo Seo , Byung-Hoon Lee , Young-Sam Lee , Jung Hyun Kweon , and Sung Bae Lee
Mol. Cells 2020; 43(9): 821-830  https://doi.org/10.14348/molcells.2020.0130 PDF PubMed Supplementary File(s) Google Scholar Search
Crystal Structure of β-Carbonic Anhydrase CafA from the Fungal Pathogen Aspergillus fumigatus
Subin Kim , Jungyoon Yeon , Jongmin Sung , and Mi Sun Jin *
Mol. Cells 2020; 43(9): 831-840  https://doi.org/10.14348/molcells.2020.0168 PDF PubMed Google Scholar Search
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Current Issue

30 September 2020
Volume 43,
Number 9,
pp. 763~840
dRAGging Amino Acid-mTORC1 Signaling by SH3BP4
Young-Mi Kim, and Do-Hyung Kim*
Received September 19, 2012; Accepted December 4, 2012.
Olfactory Carbon Dioxide Detection by Insects and Other Animals
Walton Jones
Received January 30, 2013; Accepted February 2, 2013.
Broad Activity against Porcine Bacterial Pathogens Displayed by Two Insect Antimicrobial Peptides Moricin and Cecropin B
Han Hu, Chunmei Wang, Xiaozhen Guo, Wentao Li, Yang Wang, and Qigai He
Received May 4, 2012; Accepted November 20, 2012.
A MAP Kinase Pathway Is Implicated in the Pseudohyphal Induction by Hydrogen Peroxide in Candica albicans
Kavitha Srinivasa, Jihyun Kim, Subog Yee, Wankee Kim*, and Wonja Choi*
Activation of Rice nicotianamine synthase 2 (OsNAS2) Enhances Iron Availability for Biofortification
Sichul Lee, You-Sun Kim, Un Sil Jeon, Yoon-Keun Kim, Jan K. Schjoerring, and Gynheung An*
Rhythmic Oscillation of Histone Acetylation and Methylation at the Arabidopsis Central Clock Loci
Hae-Ryong Song, and Yoo-Sun Noh*


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