• Minireview  31 March 2017

    Functional Enhancers As Master Regulators of Tissue-Specific Gene Regulation and Cancer Development

    Tissue-specific transcription is critical for normal development, and abnormalities causing undesirable gene expression may lead to diseases such as cancer. Such highly organized transcription is controlled by enhancers with specific DNA sequences recognized by transcription factors. Enhancers are associated with chromatin modifications that are distinct epigenetic features in a tissue-specific manner. Recently, super-enhancers comprising enhancer clusters co-occupied by lineage-specific fact ...

  • Article  31 March 2017

    A Role of Central NELL2 in the Regulation of Feeding Behavior in Rats

    A brain-enriched secreting signal peptide, NELL2, has been suggested to play multiple roles in the development, survival, and activity of neurons in mammal. We investigated here a possible involvement of central NELL2 in regulating feeding behavior and metabolism. In situ hybridization and an im-munohistochemical approach were used to determine expression of NELL2 as well as its colocalization with proopiomelanocortin (POMC) and neuropeptide Y (NPY) in the rat hypothalamus. T ...

  • Minireview  31 March 2017

    Signaling Pathways Controlling Microglia Chemotaxis

    Microglia are the primary resident immune cells of the central nervous system (CNS). They are the first line of defense of the brain’s innate immune response against infection, injury, and diseases. Microglia respond to extracellular signals and engulf unwanted neuronal debris by phagocytosis, thereby maintaining normal cellular homeostasis in the CNS. Pathological stimuli such as neuronal injury induce transformation and activation of resting microglia with ramified morphology into a motil ...

  • Article  31 March 2017

    Arabidopsis MAP3K16 and Other Salt-Inducible MAP3Ks Regulate ABA Response Redundantly

    In the Arabidopsis genome, approximately 80 MAP3Ks (mitogen-activated protein kinase kinase kinases) have been identified. However, only a few of them have been characterized, and the functions of most MAP3Ks are largely unknown. In this paper, we report the function of MAP3K16 and several other MAP3Ks, MAP3K14/15/17/18, whose expression is salt-inducible. We prepared MAP3K16 overexpression (OX) lines and analyzed their phenotypes. The result showed that the transgenic plants ...


Mol. Cells 2017; 40(3): 163~242
Minireviews
Signaling Pathways Controlling Microglia Chemotaxis
Yang Fan, Lirui Xie, and Chang Y. Chung
Mol. Cells 2017; 40(3): 163-168  https://doi.org/10.14348/molcells.2017.0011 PDF PubMed PubMed Central PubReader Google Scholar Search
Functional Enhancers As Master Regulators of Tissue-Specific Gene Regulation and Cancer Development
Je Yeong Ko, Sumin Oh, and Kyung Hyun Yoo
Mol. Cells 2017; 40(3): 169-177  https://doi.org/10.14348/molcells.2017.0033 PDF PubMed PubMed Central PubReader Google Scholar Search
Articles
Transcription Factor OsDOF18 Controls Ammonium Uptake by Inducing Ammonium Transporters in Rice Roots
Yunfei Wu, Wenzhu Yang, Jinhuan Wei, Hyeryung Yoon, and Gynheung An
Mol. Cells 2017; 40(3): 178-185  https://doi.org/10.14348/molcells.2017.2261 PDF PubMed PubMed Central PubReader Supplementary File(s) Google Scholar Search
A Role of Central NELL2 in the Regulation of Feeding Behavior in Rats
Jin Kwon Jeong, Jae Geun Kim, Han Rae Kim, Tae Hwan Lee, Jeong Woo Park, and Byung Ju Lee
Mol. Cells 2017; 40(3): 186-194  https://doi.org/10.14348/molcells.2017.2278 PDF PubMed PubMed Central PubReader Google Scholar Search
MiR-186 Inhibited Migration of NSCLC via Targeting cdc42 and Effecting EMT Process
Ying Dong, Xintian Jin, Zhiqiang Sun, Yueming Zhao, and Xianjing Song
Mol. Cells 2017; 40(3): 195-201  https://doi.org/10.14348/molcells.2017.2291 PDF PubMed PubMed Central PubReader Supplementary File(s) Google Scholar Search
Hepatitis C Virus Nonstructural 5A Protein (HCV-NS5A) Inhibits Hepatocyte Apoptosis through the NF-κb/miR-503/bcl-2 Pathway
Zhengyuan Xie, Zhihua Xiao, and Fenfen Wang
Mol. Cells 2017; 40(3): 202-210  https://doi.org/10.14348/molcells.2017.2299 PDF PubMed PubMed Central PubReader Google Scholar Search
Transforming Growth Factor β1/Smad4 Signaling Affects Osteoclast Differentiation via Regulation of miR-155 Expression
Hongying Zhao, Jun Zhang, Haiyu Shao, Jianwen Liu, Mengran Jin, Jinping Chen, and Yazeng Huang
Mol. Cells 2017; 40(3): 211-221  https://doi.org/10.14348/molcells.2017.2303 PDF PubMed PubMed Central PubReader Google Scholar Search
Adipose-Derived Stem Cells Suppress Inflammation Induced by IL-1β through Down-Regulation of P2X7R Mediated by miR-373 in Chondrocytes of Osteoarthritis
Rilong Jin, Miaoda Shen, Liedao Yu, Xuanwei Wang, and Xiangjin Lin
Mol. Cells 2017; 40(3): 222-229  https://doi.org/10.14348/molcells.2017.2314 PDF PubMed PubMed Central PubReader Google Scholar Search
Arabidopsis MAP3K16 and Other Salt-Inducible MAP3Ks Regulate ABA Response Redundantly
Seo-wha Choi, Seul-bee Lee, Yeon-ju Na, Sun-geum Jeung, and Soo Young Kim
Mol. Cells 2017; 40(3): 230-242  https://doi.org/10.14348/molcells.2017.0002 PDF PubMed PubMed Central PubReader Supplementary File(s) Google Scholar Search
  • e-Submission
    e-Submission Old System (~2016)  e-Submission (2017~) New System
  • For review & Editor
    e-Submission Old System (~2016)  e-Submission (2017~) New System

Current Issue

31 March 2017
Volume 40,
Number 3,
pp. 163~242
dRAGging Amino Acid-mTORC1 Signaling by SH3BP4
Young-Mi Kim, and Do-Hyung Kim*
Received September 19, 2012; Accepted December 4, 2012.
Olfactory Carbon Dioxide Detection by Insects and Other Animals
Walton Jones
Received January 30, 2013; Accepted February 2, 2013.
Broad Activity against Porcine Bacterial Pathogens Displayed by Two Insect Antimicrobial Peptides Moricin and Cecropin B
Han Hu, Chunmei Wang, Xiaozhen Guo, Wentao Li, Yang Wang, and Qigai He
Received May 4, 2012; Accepted November 20, 2012.
A MAP Kinase Pathway Is Implicated in the Pseudohyphal Induction by Hydrogen Peroxide in Candica albicans
Kavitha Srinivasa, Jihyun Kim, Subog Yee, Wankee Kim*, and Wonja Choi*
Activation of Rice nicotianamine synthase 2 (OsNAS2) Enhances Iron Availability for Biofortification
Sichul Lee, You-Sun Kim, Un Sil Jeon, Yoon-Keun Kim, Jan K. Schjoerring, and Gynheung An*
Rhythmic Oscillation of Histone Acetylation and Methylation at the Arabidopsis Central Clock Loci
Hae-Ryong Song, and Yoo-Sun Noh*

Indexed in

This journal is indexed in Science Citation Index, Scopus, Current Contents®/Life Science, Sci-search®, Research Alert®, Index Medicus, Chemical Abstract Service, and PubMed.

Manuscript Submission

To submit a manuscript, please visit the Molecules and Cells e-submission management system at http://www.ksmcb.or.kr/submission/Login.html, read the Instructions to Authors, and log into the Molecules and Cells e-submission system. For assistance with manuscript submission, please contact: admin@molcells.org.