• Minireview  31 March 2017

    Functional Enhancers As Master Regulators of Tissue-Specific Gene Regulation and Cancer Development

    Tissue-specific transcription is critical for normal development, and abnormalities causing undesirable gene expression may lead to diseases such as cancer. Such highly organized transcription is controlled by enhancers with specific DNA sequences recognized by transcription factors. Enhancers are associated with chromatin modifications that are distinct epigenetic features in a tissue-specific manner. Recently, super-enhancers comprising enhancer clusters co-occupied by lineage-specific fact ...

  • Article  31 March 2017

    A Role of Central NELL2 in the Regulation of Feeding Behavior in Rats

    A brain-enriched secreting signal peptide, NELL2, has been suggested to play multiple roles in the development, survival, and activity of neurons in mammal. We investigated here a possible involvement of central NELL2 in regulating feeding behavior and metabolism. In situ hybridization and an im-munohistochemical approach were used to determine expression of NELL2 as well as its colocalization with proopiomelanocortin (POMC) and neuropeptide Y (NPY) in the rat hypothalamus. T ...

  • Minireview  31 March 2017

    Signaling Pathways Controlling Microglia Chemotaxis

    Microglia are the primary resident immune cells of the central nervous system (CNS). They are the first line of defense of the brain’s innate immune response against infection, injury, and diseases. Microglia respond to extracellular signals and engulf unwanted neuronal debris by phagocytosis, thereby maintaining normal cellular homeostasis in the CNS. Pathological stimuli such as neuronal injury induce transformation and activation of resting microglia with ramified morphology into a motil ...

  • Article  31 March 2017

    Arabidopsis MAP3K16 and Other Salt-Inducible MAP3Ks Regulate ABA Response Redundantly

    In the Arabidopsis genome, approximately 80 MAP3Ks (mitogen-activated protein kinase kinase kinases) have been identified. However, only a few of them have been characterized, and the functions of most MAP3Ks are largely unknown. In this paper, we report the function of MAP3K16 and several other MAP3Ks, MAP3K14/15/17/18, whose expression is salt-inducible. We prepared MAP3K16 overexpression (OX) lines and analyzed their phenotypes. The result showed that the transgenic plants ...

Mol. Cells 2017; 40(4): 243~314
The Ciliary Transition Zone: Finding the Pieces and Assembling the Gate
João Gonçalves, and Laurence Pelletier
Mol. Cells 2017; 40(4): 243-253  https://doi.org/10.14348/molcells.2017.0054 PDF PubMed PubMed Central PubReader Google Scholar Search
MicroRNA-296-5p Promotes Invasiveness through Downregulation of Nerve Growth Factor Receptor and Caspase-8
Hong Lee, Chang Hoon Shin, Hye Ree Kim, Kyung Hee Choi, and Hyeon Ho Kim
Mol. Cells 2017; 40(4): 254-261  https://doi.org/10.14348/molcells.2017.2270 PDF PubMed PubMed Central PubReader Google Scholar Search
Identification and Expression of Equine MER-Derived miRNAs
Jeong-An Gim, and Heui-Soo Kim
Mol. Cells 2017; 40(4): 262-270  https://doi.org/10.14348/molcells.2017.2295 PDF PubMed PubMed Central PubReader Supplementary File(s) Google Scholar Search
Mind Bomb-Binding Partner RanBP9 Plays a Contributory Role in Retinal Development
Kyeong-Won Yoo, Maivannan Thiruvarangan, Yun-Mi Jeong, Mi-Sun Lee, Sateesh Maddirevula, Myungchull Rhee, Young-Ki Bae, Hyung-Goo Kim, and Cheol-Hee Kim
Mol. Cells 2017; 40(4): 271-279  https://doi.org/10.14348/molcells.2017.2308 PDF PubMed PubMed Central PubReader Google Scholar Search
Neuroprotective Effects of Protein Tyrosine Phosphatase 1B Inhibition against ER Stress-Induced Toxicity
Yu-Mi Jeon, Shinrye Lee, Seyeon Kim, Younghwi Kwon, Kiyoung Kim, Chang Geon Chung, Seongsoo Lee, Sung Bae Lee, and Hyung-Jun Kim
Mol. Cells 2017; 40(4): 280-290  https://doi.org/10.14348/molcells.2017.2320 PDF PubMed PubMed Central PubReader Google Scholar Search
Down-Regulation of MicroRNA-210 Confers Sensitivity towards 1’S-1’-Acetoxychavicol Acetate (ACA) in Cervical Cancer Cells by Targeting SMAD4
Neoh Hun Phuah, Mohamad Nurul Azmi, Khalijah Awang, and Noor Hasima Nagoor
Mol. Cells 2017; 40(4): 291-298  https://doi.org/10.14348/molcells.2017.2285 PDF PubMed PubMed Central PubReader Google Scholar Search
Crystal Structure of the Regulatory Domain of AphB from Vibrio vulnificus, a Virulence Gene Regulator
Nohra Park, Saemee Song, Garam Choi, Kyung Ku Jang, Inseong Jo, Sang Ho Choi, and Nam-Chul Ha
Mol. Cells 2017; 40(4): 299-306  https://doi.org/10.14348/molcells.2017.0015 PDF PubMed PubMed Central PubReader Supplementary File(s) Google Scholar Search
Caloric Restriction-Induced Extension of Chronological Lifespan Requires Intact Respiration in Budding Yeast
Young-Yon Kwon, Sung-Keun Lee, and Cheol-Koo Lee
Mol. Cells 2017; 40(4): 307-313  https://doi.org/10.14348/molcells.2017.2279 PDF PubMed PubMed Central PubReader Google Scholar Search
Erratum to: Genes Frequently Coexpressed with Hoxc8 Provide Insight into the Discovery of Target Genes
Kalyani Ruthala, Ji-Yeon Lee, Hyehyun Min, Heejei Yoon, and Myoung Hee Kim
Mol. Cells 2017; 40(4): 314-314  https://doi.org/10.14348/molcells.2017.1311 PDF PubMed PubMed Central PubReader Google Scholar Search
  • e-Submission
    e-Submission Old System (~2016)  e-Submission (2017~) New System
  • For review & Editor
    e-Submission Old System (~2016)  e-Submission (2017~) New System

Current Issue

30 April 2017
Volume 40,
Number 4,
pp. 243~314
dRAGging Amino Acid-mTORC1 Signaling by SH3BP4
Young-Mi Kim, and Do-Hyung Kim*
Received September 19, 2012; Accepted December 4, 2012.
Olfactory Carbon Dioxide Detection by Insects and Other Animals
Walton Jones
Received January 30, 2013; Accepted February 2, 2013.
Broad Activity against Porcine Bacterial Pathogens Displayed by Two Insect Antimicrobial Peptides Moricin and Cecropin B
Han Hu, Chunmei Wang, Xiaozhen Guo, Wentao Li, Yang Wang, and Qigai He
Received May 4, 2012; Accepted November 20, 2012.
A MAP Kinase Pathway Is Implicated in the Pseudohyphal Induction by Hydrogen Peroxide in Candica albicans
Kavitha Srinivasa, Jihyun Kim, Subog Yee, Wankee Kim*, and Wonja Choi*
Activation of Rice nicotianamine synthase 2 (OsNAS2) Enhances Iron Availability for Biofortification
Sichul Lee, You-Sun Kim, Un Sil Jeon, Yoon-Keun Kim, Jan K. Schjoerring, and Gynheung An*
Rhythmic Oscillation of Histone Acetylation and Methylation at the Arabidopsis Central Clock Loci
Hae-Ryong Song, and Yoo-Sun Noh*

Indexed in

This journal is indexed in Science Citation Index, Scopus, Current Contents®/Life Science, Sci-search®, Research Alert®, Index Medicus, Chemical Abstract Service, and PubMed.

Manuscript Submission

To submit a manuscript, please visit the Molecules and Cells e-submission management system at http://www.ksmcb.or.kr/submission/Login.html, read the Instructions to Authors, and log into the Molecules and Cells e-submission system. For assistance with manuscript submission, please contact: admin@molcells.org.