• Minireview  30 April 2016

    Structural and Mechanistic Insights into the Tropism of Epstein-Barr Virus

    Epstein-Barr virus (EBV) is the prototypical γ-herpesvirus and an obligate human pathogen that infects mainly epithelial cells and B cells, which can result in malignancies. EBV infects these target cells by fusing with the viral and cellular lipid bilayer membranes using multiple viral factors and host receptor(s) thus exhibiting a unique complexity in its entry machinery. To enter epithelial cells, EBV requires minimally the conserved core fusion machinery comprised of the glycoproteins gH ...

  • Article  30 April 2016

    A Systematic Analysis of Drosophila Regulatory Peptide Expression in Enteroendocrine Cells

    The digestive system is gaining interest as a major regulator of various functions including immune defense, nutrient accumulation, and regulation of feeding behavior, aside from its conventional function as a digestive organ. The Drosophila midgut epithelium is completely renewed every 1–2 weeks due to differentiation of pluripotent intestinal stem cells in the midgut. Intestinal stem cells constantly divide and differentiate into enterocytes that secrete digestive enzymes ...

  • Article  30 April 2016

    Design of a RANK-Mimetic Peptide Inhibitor of Osteoclastogenesis with Enhanced RANKL-Binding Affinity

    The receptor activator of nuclear factor κB (RANK) and its ligand RANKL are key regulators of osteoclastogenesis and well-recognized targets in developing treatments for bone disorders associated with excessive bone resorption, such as osteoporosis. Our previous work on the structure of the RANK-RANKL complex revealed that Loop3 of RANK, specifically the non-canonical disulfide bond at the tip, performs a crucial role in specific recognition of RANKL. It also demonstrated that peptide mimics ...

  • Minireview  30 April 2016

    Alternative Polyadenylation of mRNAs: 3′-Untranslated Region Matters in Gene Expression

    Almost all of eukaryotic mRNAs are subjected to polyadenylation during mRNA processing. Recent discoveries showed that many of these mRNAs contain more than one polyadenylation sites in their 3′ untranslated regions (UTR) and that alternative polyadenylation (APA) is prevalent among these genes. Many biological processes such as differentiation, proliferation, and tumorigenesis have been correlated to global APA events in the 3′ UTR of mRNAs, suggesting that these APA events are tightly r ...


Mol. Cells 2016; 39(4): 281~366
Minireviews
Alternative Polyadenylation of mRNAs: 3′-Untranslated Region Matters in Gene Expression
Hsin-Sung Yeh, and Jeongsik Yong
Mol. Cells 2016; 39(4): 281-285  http://dx.doi.org/10.14348/molcells.2016.0035 PDF PubMed PubReader Google Scholar Search
Structural and Mechanistic Insights into the Tropism of Epstein-Barr Virus
Britta S. Möhl, Jia Chen, Karthik Sathiyamoorthy, Theodore S. Jardetzky, and Richard Longnecker
Mol. Cells 2016; 39(4): 286-291  http://dx.doi.org/10.14348/molcells.2016.0066 PDF PubMed PubReader Google Scholar Search
Articles
Endothelial Aquaporin-1 (AQP1) Expression Is Regulated by Transcription Factor Mef2c
Yong Jiang, He Liu, Wen-jing Liu, Hai-bin Tong, Chang-jun Chen, Fu-gui Lin, Yan-hang Zhuo, Xiao-zhen Qian, Zeng-bin Wang, Yu Wang, Peng Zhang, and Hong-liang Jia
Mol. Cells 2016; 39(4): 292-298  http://dx.doi.org/10.14348/molcells.2016.2223 PDF PubMed PubReader Google Scholar Search
miR-30a Regulates the Expression of CAGE and p53 and Regulates the Response to Anti-Cancer Drugs
Deokbum Park, Hyuna Kim, Youngmi Kim, and Dooil Jeoung
Mol. Cells 2016; 39(4): 299-309  http://dx.doi.org/10.14348/molcells.2016.2242 PDF PubMed PubReader Google Scholar Search
Gustatory Receptors Required for Avoiding the Toxic Compound Coumarin in Drosophila melanogaster
Seeta Poudel, and Youngseok Lee
Mol. Cells 2016; 39(4): 310-315  http://dx.doi.org/10.14348/molcells.2016.2250 PDF PubMed PubReader Google Scholar Search
Design of a RANK-Mimetic Peptide Inhibitor of Osteoclastogenesis with Enhanced RANKL-Binding Affinity
Jeonghwan Hur, Ambarnil Ghosh, Kabsun Kim, Hai Minh Ta, Hyunju Kim, Nacksung Kim, Hye-Yeon Hwang, and Kyeong Kyu Kim
Mol. Cells 2016; 39(4): 316-321  http://dx.doi.org/10.14348/molcells.2016.2286 PDF PubMed PubReader Google Scholar Search
Dual Regulation of R-Type CaV2.3 Channels by M1 Muscarinic Receptors
Jin-Young Jeong, Hae-Jin Kweon, and Byung-Chang Suh
Mol. Cells 2016; 39(4): 322-329  http://dx.doi.org/10.14348/molcells.2016.2292 PDF PubMed PubReader Google Scholar Search
Long Non-Coding RNA CCAT1 Acts as a Competing Endogenous RNA to Regulate Cell Growth and Differentiation in Acute Myeloid Leukemia
Lianxiang Chen, Wei Wang, Lixia Cao, Zhijun Li, and Xing Wang
Mol. Cells 2016; 39(4): 330-336  http://dx.doi.org/10.14348/molcells.2016.2308 PDF PubMed PubReader Google Scholar Search
Attenuation of Postischemic Genomic Alteration by Mesenchymal Stem Cells: a Microarray Study
Chunggab Choi, Seung-Hun Oh, Jeong-Eun Noh, Yong-Woo Jeong, Soonhag Kim, Jung Jae Ko, Ok-Joon Kim, and Jihwan Song
Mol. Cells 2016; 39(4): 337-344  http://dx.doi.org/10.14348/molcells.2016.2317 PDF PubMed PubReader Supplementary File(s) Google Scholar Search
Let-7c miRNA Inhibits the Proliferation and Migration of Heat-Denatured Dermal Fibroblasts Through Down-Regulating HSP70
Tao Jiang, Xingang Wang, Weiwei Wu, Fan Zhang, and Shifeng Wu
Mol. Cells 2016; 39(4): 345-351  http://dx.doi.org/10.14348/molcells.2016.2336 PDF PubMed PubReader Supplementary File(s) Google Scholar Search
xCyp26c Induced by Inhibition of BMP Signaling Is Involved in Anterior-Posterior Neural Patterning of Xenopus laevis
Saet-Byeol Yu, Zobia Umair, Shiv Kumar, Unjoo Lee, Seung-Hwan Lee, Jong-Il Kim, SungChan Kim, Jae-Bong Park, Jae-Yong Lee, and Jaebong Kim
Mol. Cells 2016; 39(4): 352-357  http://dx.doi.org/10.14348/molcells.2016.0006 PDF PubMed PubReader Google Scholar Search
A Systematic Analysis of Drosophila Regulatory Peptide Expression in Enteroendocrine Cells
Ji Chen, Seol-min Kim, and Jae Young Kwon
Mol. Cells 2016; 39(4): 358-366  http://dx.doi.org/10.14348/molcells.2016.0014 PDF PubMed PubReader Supplementary File(s) Google Scholar Search
  • e-Submission
  • For review & Editor

Current Issue

30 April 2016
Volume 39,
Number 4,
pp. 281~366
Olfactory Carbon Dioxide Detection by Insects and Other Animals
Walton Jones
Received January 30, 2013; Accepted February 2, 2013.
dRAGging Amino Acid-mTORC1 Signaling by SH3BP4
Young-Mi Kim, and Do-Hyung Kim*
Received September 19, 2012; Accepted December 4, 2012.
Broad Activity against Porcine Bacterial Pathogens Displayed by Two Insect Antimicrobial Peptides Moricin and Cecropin B
Han Hu, Chunmei Wang, Xiaozhen Guo, Wentao Li, Yang Wang, and Qigai He
Received May 4, 2012; Accepted November 20, 2012.
A MAP Kinase Pathway Is Implicated in the Pseudohyphal Induction by Hydrogen Peroxide in Candica albicans
Kavitha Srinivasa, Jihyun Kim, Subog Yee, Wankee Kim*, and Wonja Choi*
Activation of Rice nicotianamine synthase 2 (OsNAS2) Enhances Iron Availability for Biofortification
Sichul Lee, You-Sun Kim, Un Sil Jeon, Yoon-Keun Kim, Jan K. Schjoerring, and Gynheung An*
Rhythmic Oscillation of Histone Acetylation and Methylation at the Arabidopsis Central Clock Loci
Hae-Ryong Song, and Yoo-Sun Noh*

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