• Research Article  31 August 2020

    Evolutionary and Functional Analysis of Korean Native Pig Using Single Nucleotide Polymorphisms

    Time and cost-effective production of next-generation sequencing data has enabled the performance of population-scale comparative and evolutionary studies for various species, which are essential for obtaining the comprehensive insight into molecular mechanisms underlying species- or breed-specific traits. In this study, the evolutionary and functional analysis of Korean native pig (KNP) was performed using single nucleotide polymorphism (SNP) data by comparative and population genomic approache ...

  • Research Article  31 August 2020

    WD Repeat Domain 1 Deficiency Inhibits Neointima Formation in Mice Carotid Artery by Modulation of Smooth Muscle Cell Migration and Proliferation

    The migration, dedifferentiation, and proliferation of vascular smooth muscle cells (VSMCs) are responsible for intimal hyperplasia, but the mechanism of this process has not been elucidated. WD repeat domain 1 (WDR1) promotes actin-depolymerizing factor (ADF)/cofilin-mediated depolymerization of actin filaments (F-actin). The role of WDR1 in neointima formation and progression is still unknown. A model of intimal thickening was constructed by ligating the left common carotid artery in Wdr1

  • Research Article  31 August 2020

    Cleavage-Dependent Activation of ATP-Dependent Protease HslUV from Staphylococcus aureus

    HslUV is a bacterial heat shock protein complex consisting of the AAA+ ATPase component HslU and the protease component HslV. HslV is a threonine (Thr) protease employing the N-terminal Thr residue in the mature protein as the catalytic residue. To date, HslUV from Gram-negative bacteria has been extensively studied. However, the mechanisms of action and activation of HslUV from Gram-positive bacteria, which have an additional N-terminal sequence before the catalytic Thr residue, remain to be re ...

  • Minireview  31 August 2020

    Lipophagy: Molecular Mechanisms and Implications in Metabolic Disorders

    Autophagy is an intracellular degradation system that breaks down damaged organelles or damaged proteins using intracellular lysosomes. Recent studies have also revealed that various forms of selective autophagy play specific physiological roles under different cellular conditions. Lipid droplets, which are mainly found in adipocytes and hepatocytes, are dynamic organelles that store triglycerides and are critical to health. Lipophagy is a type of selective autophagy that targets lipid droplets ...


Mol. Cells 2020; 43(8): 671~762
Minireviews
Regulator of Calcineurin (RCAN): Beyond Down Syndrome Critical Region
Sun-Kyung Lee and Joohong Ahnn
Mol. Cells 2020; 43(8): 671-685  https://doi.org/10.14348/molcells.2020.0060 PDF PubMed PubMed Central PubReader Google Scholar Search
Lipophagy: Molecular Mechanisms and Implications in Metabolic Disorders
Dong Wook Shin
Mol. Cells 2020; 43(8): 686-693  https://doi.org/10.14348/molcells.2020.0046 PDF PubMed PubMed Central PubReader Google Scholar Search
Research Articles
Cleavage-Dependent Activation of ATP-Dependent Protease HslUV from Staphylococcus aureus
Soyeon Jeong , Jinsook Ahn , Ae-Ran Kwon , and Nam-Chul Ha
Mol. Cells 2020; 43(8): 694-704  https://doi.org/10.14348/molcells.2020.0074 PDF PubMed PubMed Central PubReader Supplementary File(s) Google Scholar Search
Mislocalization of TORC1 to Lysosomes Caused by KIF11 Inhibition Leads to Aberrant TORC1 Activity
Yoon-Gu Jang , Yujin Choi , Kyoungho Jun , and Jongkyeong Chung
Mol. Cells 2020; 43(8): 705-717  https://doi.org/10.14348/molcells.2020.0089 PDF PubMed PubMed Central PubReader Supplementary File(s) Google Scholar Search
LncRNA CRNDE Promotes the Progression of B-cell Precursor Acute Lymphoblastic Leukemia by Targeting the miR-345-5p/CREB Axis
Weimin Wang , Feifei Wu , Ping Ma , Silin Gan , Xue Li , Li Chen , Ling Sun , Hui Sun , Zhongxing Jiang , and Feng Guo
Mol. Cells 2020; 43(8): 718-727  https://doi.org/10.14348/molcells.2020.0065 PDF PubMed PubMed Central PubReader Supplementary File(s) Google Scholar Search
Evolutionary and Functional Analysis of Korean Native Pig Using Single Nucleotide Polymorphisms
Jongin Lee , Nayoung Park , Daehwan Lee , and Jaebum Kim
Mol. Cells 2020; 43(8): 728-738  https://doi.org/10.14348/molcells.2020.0040 PDF PubMed PubMed Central PubReader Supplementary File(s) Google Scholar Search
NFI-C Is Required for Epiphyseal Chondrocyte Proliferation during Postnatal Cartilage Development
Dong-Seol Lee , Song Yi Roh , Hojae Choi , and Joo-Cheol Park
Mol. Cells 2020; 43(8): 739-748  https://doi.org/10.14348/molcells.2020.2272 PDF PubMed PubMed Central PubReader Supplementary File(s) Google Scholar Search
WD Repeat Domain 1 Deficiency Inhibits Neointima Formation in Mice Carotid Artery by Modulation of Smooth Muscle Cell Migration and Proliferation
JiSheng Hu , ShangJing Pi , MingRui Xiong , ZhongYing Liu , Xia Huang , Ran An , TongCun Zhang , and BaiYin Yuan
Mol. Cells 2020; 43(8): 749-762  https://doi.org/10.14348/molcells.2020.0085 PDF PubMed PubMed Central PubReader Google Scholar Search
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Current Issue

31 August 2020
Volume 43,
Number 8,
pp. 671~762
dRAGging Amino Acid-mTORC1 Signaling by SH3BP4
Young-Mi Kim, and Do-Hyung Kim*
Received September 19, 2012; Accepted December 4, 2012.
Olfactory Carbon Dioxide Detection by Insects and Other Animals
Walton Jones
Received January 30, 2013; Accepted February 2, 2013.
Broad Activity against Porcine Bacterial Pathogens Displayed by Two Insect Antimicrobial Peptides Moricin and Cecropin B
Han Hu, Chunmei Wang, Xiaozhen Guo, Wentao Li, Yang Wang, and Qigai He
Received May 4, 2012; Accepted November 20, 2012.
A MAP Kinase Pathway Is Implicated in the Pseudohyphal Induction by Hydrogen Peroxide in Candica albicans
Kavitha Srinivasa, Jihyun Kim, Subog Yee, Wankee Kim*, and Wonja Choi*
Activation of Rice nicotianamine synthase 2 (OsNAS2) Enhances Iron Availability for Biofortification
Sichul Lee, You-Sun Kim, Un Sil Jeon, Yoon-Keun Kim, Jan K. Schjoerring, and Gynheung An*
Rhythmic Oscillation of Histone Acetylation and Methylation at the Arabidopsis Central Clock Loci
Hae-Ryong Song, and Yoo-Sun Noh*


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