Molecules and Cells

Indexed in /covered by CAS, KoreaScience & DOI/Crossref:eISSN 0219-1032   pISSN 1016-8478

Fig. 2.

Download original image
Fig. 2. Differentiation of SARS-CoV-2-specific CD8+ T cells during the convalescent period of COVID-19. From the early convalescent to the late convalescent phases, the frequency of SARS-CoV-2-specific CD8+ T cells expressing CD38 and PD-1 decreases gradually, whereas the frequency of SARS-CoV-2-specific CD8+ T cells expressing CCR7, CD45RA, and CD127 increases. In particular, among SARS-CoV-2-specific CD8+ T cells, the frequency of CCR7+CD45RA+CD95+ stem cell-like memory T (TSCM) cells that have the capacity for self-renewal and multipotency increases in the late convalescent phase. The generation of TSCM cells is also observed among SARS-CoV-2-specific CD4+ T cells.
Mol. Cells 2021;44:401~407 https://doi.org/10.14348/molcells.2021.0079
© Mol. Cells