Fig. 3. Effect of HOXA11-AS on the cisplatin resistance of NPC cells. (A) Expression of HOXA11-AS and miR-454-3p in NPC parental cells (C666-1 and HNE1) and cisplatin-resistant cells (C666-1/DDP and HNE1/DDP) was assessed by qRT-PCR; different letters indicate the statistical significance among the groups, P < 0.05, and the same letters indicate no statistical significance among the groups, P > 0.05. (B) Cell viabilities and IC₅₀ values of NPC parental cells (C666-1 and HNE1) and cisplatin-resistant cells (C666-1/DDP and HNE1/DDP) after treatment with DDP at varying concentrations, as assessed by MTT assay.

Mol. Cells 2020;43:856~869 https://doi.org/10.14348/molcells.2020.0133

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