Molecules and Cells

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Fig. 1.

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Fig. 1. Expression of HOXA11-AS and miR-454-3p in NPC tissues and drug-resistant cell lines. (A and B) Expression of HOXA11-AS (A) and miR-454-3p (B) in NPC tissues and tumor-adjacent normal tissues; *P < 0.05 vs the tumor-adjacent normal tissues. (C) The expression level of HOXA11-AS in HNSCC tissues and normal tissues in The Cancer Genome Atlas (TCGA) database was analyzed and is shown. (D) The survival curve was generated to analyze the correlation between HOXA11-AS expression and the overall survival of HNSCC patients based on TCGA dataset. (E and F) Viabilities and IC50 values of HNE1, C666-1, HNE1/DDP, and C666-1/DDP cells treated with DDP at varying concentration as assessed by MTT. (G and H) Expression of HOXA11-AS and miR-454-3p in NPC cells (HNE1, C666-1) and the corresponding cisplatin-resistant cells (HNE1/DDP, C666-1/DDP); *P < 0.05 vs HNE1 or C666-1 cells.
Mol. Cells 2020;43:856~869 https://doi.org/10.14348/molcells.2020.0133
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