Molecules and Cells

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Fig. 4.

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Fig. 4. Expression of HOTTIP and Hox13 was measured in mouse tissues with and without p53 in vivo have been shown in (A). Total RNA was isolated from p53 +/+ mouse tissues and p53 −/− mouse tissues, and then RT-qPCR was used to measure HOTTIP and Hoxa13. (B and C) p53 promotes the expression of HOTTIP and Hoxa13 in vitro. GC-1 cells were transfected with pcDNA3.1(+)/pcDNA3.1(+)-Hoxa13 (B) or si-NC/si-p53 (C). Isolated RNA was analyzed using RT-qPCR after 24-h post transfection. (A–C) Data are presented as the mean ± SEM of three independent experiments, each performed in triplicate. *P < 0.05.
Mol. Cells 2019;42:794~803
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