Molecules and Cells

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Fig. 4.

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Fig. 4. (A) The ratio of progerin to lamin A as a criterion to determine disease severity in HGPS. (**P < 0.01, one-way ANOVA followed by Bonferroni’s multiple comparison test). Means ± S.D., N = 3. (B) Measurement of abnormal nuclear structures (red: lamin A/C, arrow head: abnormal nuclear structure, scale bar: 5 μm). N = 200. Cells were treated with DMSO or 0.5 μM KU-60019 for 14 days.
Mol. Cells 2019;42:210~217
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