Molecules and Cells

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Fig. 4.

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Fig. 4. Cellular stimuli induce signaling cascades and metabolic reprogramming, leading to the modification of epigenetic regulators and transcription factors at multiple levels, such as posttranslational modifications or the availability of metabolites. Subsequent epigenetic changes targeted by the epigenetic regulators, along with interacting transcription factors, mediate cellular adaptations to the given stimuli by modulating gene expressions.
Mol. Cells 2018;41:264~270 https://doi.org/10.14348/molcells.2018.0076
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