Molecules and Cells

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Fig. 3.

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Fig. 3. Quercetin enhanced cisplatin sensitivity of 143B osteosarcoma cells by raising miR-217 level. (A) MiR-217 expression upon quercetin and/or cisplatin treatment. (B) KRAS protein and mRNA expression upon quercetin and/or cisplatin treatment. (C, D) The effects of miR-217 overexpression or knockdown on cell viability under varying treatments. Cells were treated with 5 μM cisplatin and 5 μM quercetin for 24 h. Quercetin was dissolved in water with 0.5% (v/v) ethanol. Water with 0.5% ethanol was used for the control. In cell transfection, 100 nM mimic or antagomir was used for 24 h. Afterwards, cisplatin and/or quercetin treatments were performed.
Mol. Cells 2015;38:638~642
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